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[Description of 165 Episodes of Fungemia: A Multicenter Study.]

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Specialty Microbiology
Date 2008 May 14
PMID 18473589
Citations 3
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Abstract

Unlabelled: The aim of this article is to describe the main features of fungemia belonged to the Multicenter Study Sepsis Data realised in 34 spanish hospitals. The hospitals were been given a protocol and a software specially designed for this study. 165 episodes of fungemia has been recovered (total: 5,000 episodes of bacteremia). The main results are showed as follows. Sex: male 100 (60.6%); female 65 (39.4%). Areas: medical 64 (38.8%); intensive care unit 48 (29.1%); surgical 39 (23.6%); paediatric 14 (8.5%). Underlying disease: neoplasia 43 (26.1%); HIV infection 28 (16.9%); chronic obtructive pulmonary disease 18 (10.9%); diabetes mellitus and parenteral drug abuse 15 (9.1%) every one. Nosocomial fungemia: 119 (72.1%). Community-acquired fungemia: 42 (25.5%).

Sources: primary 41 (24.9%); catheter 40 (24.2%); respiratory 23 (13.9%); urinary 17 (10.3%); abdominal 8 (4.9%); skin/soft tissues 4 (4.4%); surgical wound 6 (3.6%). Fungi most often isolated: Candida albicans, 73 isolates (44.2%); Candida parapsilosis, 20 (12.1%); Cryptococcus spp., 12 (7.3%) and Candida glabrata, 6 (3.6%). Polymicrobial fungemia: 19 (11.5%). Fluconazole (54.4%) and amphotericin B (41.9%) were the antifungal agents most often used. Mortality: 33.3%.

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