Efficacy and Tolerance of Single-dose Azithromycin for Treatment of Chlamydial Cervicitis During Pregnancy

Overview

Journal Infect Dis Obstet Gynecol

Publisher Wiley

Specialties Gynecology & Obstetrics
Infectious Diseases

Date 1995 Jan 1

PMID 18472889

Citations 4

Authors

J M Miller

Affiliations

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Abstract

Objective: The intent of this study was to determine the efficacy and tolerance of single-dose oral azithromycin in the treatment of pregnant women with endocervical chlamydial carriage.

Methods: A retrospective review of clinic records over a two-year period identified pregnant patients treated with a single 1-g dose of azithromycin for chlamydial carriage. The side effects and subsequent chlamydial carriage (test of cure) were noted.

Results: A total of 146 pregnant women treated with azithromycin was reviewed. A cure rate of 96% was found. Side effects were reported in 5%.

Conclusions: A single 1-g oral dose of azithromycin is effective for the treatment of chlamydia and is well tolerated in pregnant women.

Citing Articles

On the pathway to better birth outcomes? A systematic review of azithromycin and curable sexually transmitted infections.

Chico R, Hack B, Newport M, Ngulube E, Chandramohan D Expert Rev Anti Infect Ther. 2013; 11(12):1303-32.

PMID: 24191955 PMC: 3906303. DOI: 10.1586/14787210.2013.851601.

Open study of the safety and efficacy of a single oral dose of cefixime for the treatment of gonorrhea in pregnancy.

Miller J Infect Dis Obstet Gynecol. 1997; 5(3):259-61.

PMID: 18476147 PMC: 2364547. DOI: 10.1155/S1064744997000434.

Treatment of Chlamydia trachomatis infections in pregnant women.

Miller J, Martin D Drugs. 2000; 60(3):597-605.

PMID: 11030469 DOI: 10.2165/00003495-200060030-00006.

Concurrent gonococcal and chlamydial infection: how best to treat.

Robinson A, Ridgway G Drugs. 2000; 59(4):801-13.

PMID: 10804036 DOI: 10.2165/00003495-200059040-00006.

References

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