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Novel Approaches for the Treatment of Rheumatoid Arthritis: Lessons from the Evaluation of Synovial Biomarkers in Clinical Trials

Overview
Publisher Elsevier
Specialty Rheumatology
Date 2008 May 6
PMID 18455687
Citations 19
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Abstract

The analysis of synovial biomarkers is increasingly used in the context of innovative trial design in rheumatoid arthritis (RA). This approach, which is generally well tolerated by patients, has been used to provide insight into the pathogenesis of RA and the mechanism of action of therapy, as well as for screening purposes during early drug development.

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