Optical Coherence Tomography Predictive Factors for Macular Hole Surgery Outcome

Overview

Journal Br J Ophthalmol

Specialty Ophthalmology

Date 2008 Apr 29

PMID 18441174

Citations 73

Authors

J M Ruiz-Moreno

C Staicu

D P Pinero

J Montero

F Lugo

P Amat

Affiliations

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Abstract

Aim: To evaluate the use of preoperative optical coherence tomography (OCT) findings as predictive factors for macular hole (MH) surgery outcomes.

Methods: 46 eyes from 46 patients with a diagnosis of MH were included in this study. In all cases, a pars plana 25-gauge vitrectomy with peeling of the internal limiting membrane was performed. Before and after surgery, a complete clinical examination and a detailed macular analysis, which included the MH minimum and base diameter, the MH height, the Macular Hole Index (MHI), Diameter Hole Index (DHI) and Tractional Hole Index (THI), were performed. Predictive factors for visual prognosis after surgery were obtained by receiver operating characteristic curve analysis.

Results: Minimum and base diameter as well as THI and MHI correlated significantly (p<0.01, p = 0.01, p = 0.04, p = 0.03, respectively) with postoperative best spectacle corrected visual acuity at 3 months, but DHI and MH height did not. Cut-off values of 311 microm and 1.41 were obtained for the minimum diameter and THI, respectively, from receiver operating characteristic curve analysis, providing an acceptable sensitivity and specificity.

Conclusion: An MH minimum diameter of <311 microm or a THI >1.41 are predictive factors for a good visual prognosis after MH surgery.

Citing Articles

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Comparison of the inverted internal limiting membrane flap technique without versus with an autologous blood clot for treating macular hole-associated retinal detachment.

Zhu K, Wang Y, Lei B, Chen L, Zhang Y, Chang Q Eye Vis (Lond). 2025; 12(1):1.

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Predicting macular hole surgery outcomes: Integrating preoperative OCT features with supervised machine learning statistical models.

Venkatesh R, Gandhi P, Choudhary A, Sehgal G, Godani K, Darade S Indian J Ophthalmol. 2024; 73(Suppl 1):S66-S71.

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Predictive relevance of optical coherence tomography indices in conjunction with visual acuity and surgical outcomes of idiopathic macular hole.

Kumar S, Rao G, Sinha N, Rath B, Pattanayak S, Pal A Heliyon. 2024; 10(20):e39261.

PMID: 39640712 PMC: 11620274. DOI: 10.1016/j.heliyon.2024.e39261.

Development and preliminary evaluation of a novel preoperative index for quantitative analysis of photoreceptor loss in full-thickness macular holes.

Quarta A, Govetto A, Porreca A, Toto L, Di Nicola M, Ruggeri M Graefes Arch Clin Exp Ophthalmol. 2024; .

PMID: 39460786 DOI: 10.1007/s00417-024-06654-z.