Causes of Death in Hemolytic Uremic Syndrome
Overview
Pediatrics
Authors
Affiliations
One hundred and four children developed typical post-diarrhea hemolytic uremic syndrome (D+ HUS) over an 11-year period. Four of the children died in the acute stage. Two of the children died from a central nervous system complication which was attributable to the HUS process. One child died suddenly without any explanation. The 4th child died following a cardiovascular collapse, perhaps related to septic shock. The literature on the causes of death in children with HUS is reviewed.
Guidelines for the management and investigation of hemolytic uremic syndrome.
Igarashi T, Ito S, Sako M, Saitoh A, Hataya H, Mizuguchi M Clin Exp Nephrol. 2014; 18(4):525-57.
PMID: 25099085 DOI: 10.1007/s10157-014-0995-9.
Bauwens A, Betz J, Meisen I, Kemper B, Karch H, Muthing J Cell Mol Life Sci. 2012; 70(3):425-57.
PMID: 22766973 PMC: 11113656. DOI: 10.1007/s00018-012-1060-z.
Azithromycin decolonization of STEC--a new risk emerges.
Seifert M, Tarr P Nat Rev Nephrol. 2012; 8(7):429.
PMID: 22664737 DOI: 10.1038/nrneph.2012.87-c1.
Shringi S, Garcia A, Lahmers K, Potter K, Muthupalani S, Swennes A Infect Immun. 2011; 80(1):369-80.
PMID: 22025512 PMC: 3255674. DOI: 10.1128/IAI.05470-11.
Bacterial effector binding to ribosomal protein s3 subverts NF-kappaB function.
Gao X, Wan F, Mateo K, Callegari E, Wang D, Deng W PLoS Pathog. 2009; 5(12):e1000708.
PMID: 20041225 PMC: 2791202. DOI: 10.1371/journal.ppat.1000708.