Viral Infections

Overview

Journal J Clin Pathol Suppl (R Coll Pathol)

Specialty Pathology

Date 1976 Jan 1

PMID 184117

Citations 4

Authors

J A DUDGEON

Affiliations

Soon will be listed here.

Abstract

Although rubella is the only virus which can be regarded in the strict sense of the term a teratogen, there is no convincing evidence that other viruses can cause fetal damage of varying severity. The risk to the fetus appears to depend on the nature of the infectious agent, the maternal immune status and the gestational age when infection takes place. The possibility that subclinical maternal infections may cause damage must not be overlooked. As some of the viruses referred to can cause damage after the period of organogenesis, the use of the term 'teratogenic efect' in relation to viral infections is considered to be inappropriate.

Citing Articles

Fatal Cowpox Virus Infection in Human Fetus, France, 2017.

Ferrier A, Frenois-Veyrat G, Schvoerer E, Henard S, Jarjaval F, Drouet I Emerg Infect Dis. 2021; 27(10):2570-2577.

PMID: 34352194 PMC: 8462324. DOI: 10.3201/eid2710.204818.

Non-human Primate Models to Investigate Mechanisms of Infection-Associated Fetal and Pediatric Injury, Teratogenesis and Stillbirth.

Li M, Brokaw A, Furuta A, Coler B, Obregon-Perko V, Chahroudi A Front Genet. 2021; 12:680342.

PMID: 34290739 PMC: 8287178. DOI: 10.3389/fgene.2021.680342.

Pluripotent Stem Cell-Based Models: A Peephole into Virus Infections during Early Pregnancy.

Claus C, Jung M, Hubschen J Cells. 2020; 9(3).

PMID: 32110999 PMC: 7140399. DOI: 10.3390/cells9030542.

Examination of products of conception from previable human pregnancies.

Rushton D J Clin Pathol. 1981; 34(8):819-35.

PMID: 7024313 PMC: 493949. DOI: 10.1136/jcp.34.8.819.

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