Review: Hepatotoxicity and EGFR Inhibition
Overview
Affiliations
Hepatotoxicity of Small Molecule Protein Kinase Inhibitors for Cancer.
Vigano M, La Milia M, Grassini M, Pugliese N, De Giorgio M, Fagiuoli S Cancers (Basel). 2023; 15(6).
PMID: 36980652 PMC: 10046041. DOI: 10.3390/cancers15061766.
Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites.
Hughes T, Dang N, Kumar A, Flynn N, Swamidass S J Chem Inf Model. 2020; 60(10):4702-4716.
PMID: 32881497 PMC: 8716321. DOI: 10.1021/acs.jcim.0c00360.
Ai C, Liu Y, Li W, Chen D, Zhu X, Yan Y PLoS One. 2017; 12(6):e0179333.
PMID: 28628631 PMC: 5476264. DOI: 10.1371/journal.pone.0179333.
Metabolism considerations for kinase inhibitors in cancer treatment.
Duckett D, Cameron M Expert Opin Drug Metab Toxicol. 2010; 6(10):1175-93.
PMID: 20684746 PMC: 2940961. DOI: 10.1517/17425255.2010.506873.