Higher Risk of Adjacent Segment Degeneration After Floating Fusions: Long-term Outcome After Low Lumbar Spine Fusions
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Study Design: We report the long-term outcome after mono-segmental and bisegmental fusions at the lumbar L4-S1 region of the spine.
Objective: Long-term clinical and radiologic outcome measures were used to determine a lumbar fusion's contribution to degenerative changes in adjacent motion segments (ASD).
Summary Of Background Data: The role of low lumbar spinal fusions and their long-term contribution to accelerated degenerative changes in the adjacent motion segments continues to be a subject of controversy.
Patients And Methods: We followed-up 102 patients with an average age of 54 (22 to 78) years and a follow-up time of 14 (3 to 22) years.
Results: Overall results in patients were good, the Oswestry-Disability Index (ODI) showed an average of 26% (0% to 70%) at follow-up, the Visual Analog Scale rose from 2.7 (postoperative) and 2.9 (12 wk follow-up) to 3.6 (latest follow-up) points, respectively. Patient satisfaction with their health-related situation at follow-up was 69% (15% to 100%). Patients who underwent fusions of the segment L5/S1 showed a significant (P<0.05) lower risk for ASD than patients with fusions L4/5 (20% vs. 46%). Compared with L4/5 fusions, bisegmental L4-S1 fusions showed a similar trend (P=0.06) with a lower risk for ASD (24%). Objective and subjective clinical results showed no differences between these groups. Patients suffering from ASD showed significant (P<0.05) reduced sacral inclination and lumbar lordosis angles and also significant (P<0.05) higher ODI values compared with non-ASD patients.
Conclusions: We conclude that floating fusions of single low lumbar segments are more likely to result in ASD and are negatively influenced by sagittal plane abnormalities.
Tsujino M, Matsumura A, Ohyama S, Kato M, Namikawa T, Hori Y Eur Spine J. 2025; 34(3):1063-1070.
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Lin X, Zhu J, Song J, Wang L, Ge J, Sha W Global Spine J. 2024; :21925682241297934.
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Liu W, Ma Z, Wang Y, Yang J Bioact Mater. 2022; 23:274-299.
PMID: 36439088 PMC: 9679278. DOI: 10.1016/j.bioactmat.2022.11.006.
Chang C, Tsou H, Chang H, Chan L, Zhuo G, Maeda T Int J Mol Sci. 2022; 23(1).
PMID: 35008997 PMC: 8745749. DOI: 10.3390/ijms23010565.
Nagata K, Ando T, Sasaki K, Urayama D Int J Spine Surg. 2021; 14(6):989-995.
PMID: 33560259 PMC: 7872397. DOI: 10.14444/7148.