» Articles » PMID: 18379893

Acute Pyelonephritis with Renal Vein and Inferior Vena Cava Thrombosis in a Case of Hyperhomocysteinemia

Overview
Publisher Springer
Specialty Nephrology
Date 2008 Apr 2
PMID 18379893
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

Acute pyelonephritis is not considered a common cause of renal vein (RVT) and inferior vena caval thrombosis (IVCT). Apart from malignancy, RVT is not an uncommon condition amongst patients with nephrotic syndrome, most commonly seen in patients with membranous glomerulonephritis. However, RVT occurring in association to acute pyelonephritis is rare. Clinically, it is difficult to distinguish between acute pyelonephritis and RVT because both present with fever, flank pain, and hematuria. We report a case of acute pyelonephritis with RVT and IVCT with underlying hyperhomocysteinemia. The patient was treated with systemic anticoagulation, antibiotics, and B complex therapy. At 3 months follow-up, there was complete resolution of thrombus but the left kidney was nonfunctioning.

Citing Articles

A Rare Case of Pyelonephritis With Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia Complicated by Renal Vein Thrombosis.

Al-Anbagi U, Abdelrahman A, Al Hassan S, Mohammed N, Nashwan A, Salehi A Cureus. 2025; 17(1):e76832.

PMID: 39897252 PMC: 11787951. DOI: 10.7759/cureus.76832.


Renal Vein Thrombosis Secondary to Pyelonephritis: Targeting a Thrombo-Inflammatory Entity.

Kounatidis D, Papadimitropoulos V, Vallianou N, Poulaki A, Dimitriou K, Tsiara I Clin Pract. 2024; 14(3):1110-1122.

PMID: 38921266 PMC: 11202970. DOI: 10.3390/clinpract14030088.


Segmental renal vein thrombosis: An unusual complication of acute pyelonephritis.

Hassine M, Ben Hadj Alouane H, Oueslati M, Fassi Fihri E, Chammakhi C, Ben Rhouma S Urol Case Rep. 2023; 49:102444.

PMID: 37250968 PMC: 10220306. DOI: 10.1016/j.eucr.2023.102444.


Portal Vein Thrombosis in a Patient with Type 1 Diabetes Presenting as Acute Pyelonephritis.

Al Saeed Z, Alabdrabalnabi F, Alanazi A, Albaker W, Al-Sultan O Eur J Case Rep Intern Med. 2020; 7(3):001391.

PMID: 32206638 PMC: 7083186. DOI: 10.12890/2020_001391.


Renal vein thrombosis complicating severe acute pyelonephritis with renal abscesses and associated bacteraemia caused by extended-spectrum beta-lactamase producing Escherichia coli.

Assimakopoulos S, Kraniotis P, Gogos C, Marangos M CEN Case Rep. 2018; 7(1):90-93.

PMID: 29327131 PMC: 5886932. DOI: 10.1007/s13730-017-0301-2.


References
1.
Lam K, Lui C . Successful treatment of acute inferior vena cava and unilateral renal vein thrombosis by local infusion of recombinant tissue plasminogen activator. Am J Kidney Dis. 1998; 32(6):1075-9. DOI: 10.1016/s0272-6386(98)70086-1. View

2.
Libby P, Simon D . Inflammation and thrombosis: the clot thickens. Circulation. 2001; 103(13):1718-20. DOI: 10.1161/01.cir.103.13.1718. View

3.
Markowitz G, Brignol F, Burns E, KOENIGSBERG M, Folkert V . Renal vein thrombosis treated with thrombolytic therapy: case report and brief review. Am J Kidney Dis. 1995; 25(5):801-6. DOI: 10.1016/0272-6386(95)90558-8. View

4.
Zissin R . Nonopacification of an existing kidney on excretory urography. AJR Am J Roentgenol. 2000; 175(4):1187-8. DOI: 10.2214/ajr.175.4.1751187. View

5.
Eijsten A, Leisinger H, JUCKER A . Unilateral pyonephrosis with septic thrombosis of the renal vein and vena cava. Urol Int. 1986; 41(1):77-9. DOI: 10.1159/000281167. View