Principles in Genetic Risk Assessment

Overview

Journal Ther Clin Risk Manag

Publisher Dove Medical Press

Date 2008 Mar 25

PMID 18360538

Citations 3

Authors

Pedro Viana Baptista

Affiliations

Soon will be listed here.

Abstract

Risk assessment constitutes an essential component of genetic counseling and testing, and the genetic risk should be estimated as accurately as possible for individual and family decision making. All relevant information retrieved from population studies and pedigree and genetic testing enhances the accuracy of the assessment of an individual's genetic risk. This review will focus on the following general aspects implicated in risk assessment: the increasing genetic information regarding disease; complex traits versus Mendelian disorders; and the influence of the environment and disease susceptibility. The influence of these factors on risk assessment will be discussed.

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