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Caffey Disease with Raised Immunoglobulin Levels and Thrombocytosis

Overview
Journal Indian J Pediatr
Specialty Pediatrics
Date 2008 Mar 13
PMID 18334802
Citations 4
Authors
T Sathish Kumar
Julius Xavier Scott
Leni Grace Mathew
Affiliations
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Abstract

Infantile cortical hyperostosis (Caffey disease) is characterized by radiological evidence of cortical hyperostosis, soft tissue swellings, fever and irritability. We report a case of Caffey disease highlighting its presentation with thrombocytosis and high serum immunoglobulin level to alert physicians to use steroids cautiously in view of the known thrombocythemic effect of the drug. Raised Immunoglobulin also suggests that this syndrome could be infectious in origin.

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