Comparison and Analysis of Inter-subject Variability of Simulated Magnetic Activity Generated from Gastric Electrical Activity

Overview

Journal Ann Biomed Eng

Specialty Biomedical Engineering

Date 2008 Mar 12

PMID 18330701

Citations 11

Authors

Rie Komuro

Leo K Cheng

Andrew J Pullan

Affiliations

Soon will be listed here.

Abstract

Electrogastrograms (EGGs) produced from gastric electrical activity (GEA) are used as a non-invasive method to aid in the assessment of a subject's gastric condition. It has been documented that recordings of the magnetic activity generated from GEA are more reliable. Typically, with magnetic measurements of GEA, only activity perpendicular to the body is recorded. Also, external anatomical landmarks are used to position the magnetic recording devices, SQUIDs, (Superconducting Quantum Interference Devices) over the stomach with no allowance made for body habitus. In the work presented here, GEA and its corresponding magnetic activity are simulated. Using these data, we investigate the effects of using a standard SQUID location as well as a customized SQUID position and the contribution the magnetic component perpendicular to the body makes to the magnetic field. We also explore the effects of the stomach wall thickness on the resultant magnetic fields. The simulated results show that the thicker the wall, the larger the magnitude of the magnetic field holding the same signal patterns. We conclude that most of the magnetic activity arising from GEA occurs in a plane parallel to the anterior body. We also conclude that using a standard SQUID position can be suboptimal.

Citing Articles

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References

Aliev R, Richards W, Wikswo J . A simple nonlinear model of electrical activity in the intestine. J Theor Biol. 2000; 204(1):21-8. DOI: 10.1006/jtbi.2000.1069. View

Chen J, McCallum R . Electrogastrography: measurement, analysis and prospective applications. Med Biol Eng Comput. 1991; 29(4):339-50. DOI: 10.1007/BF02441653. View

Huh C, Bhutani M, Farfan E, Bolch W . Individual variations in mucosa and total wall thickness in the stomach and rectum assessed via endoscopic ultrasound. Physiol Meas. 2003; 24(4):N15-22. DOI: 10.1088/0967-3334/24/4/401. View

Cheng L, Komuro R, Austin T, Buist M, Pullan A . Anatomically realistic multiscale models of normal and abnormal gastrointestinal electrical activity. World J Gastroenterol. 2007; 13(9):1378-83. PMC: 4146922. DOI: 10.3748/wjg.v13.i9.1378. View

Bradshaw L, Irimia A, Sims J, Gallucci M, Palmer R, Richards W . Biomagnetic characterization of spatiotemporal parameters of the gastric slow wave. Neurogastroenterol Motil. 2006; 18(8):619-31. DOI: 10.1111/j.1365-2982.2006.00794.x. View

Buist M, Cheng L, Sanders K, Pullan A . Multiscale modelling of human gastric electric activity: can the electrogastrogram detect functional electrical uncoupling?. Exp Physiol. 2006; 91(2):383-90. DOI: 10.1113/expphysiol.2005.031021. View

Mintchev M, Kingma Y, Bowes K . Accuracy of cutaneous recordings of gastric electrical activity. Gastroenterology. 1993; 104(5):1273-80. DOI: 10.1016/0016-5085(93)90334-9. View

Adams P, Hendershot G, Marano M . Current estimates from the National Health Interview Survey, 1996. Vital Health Stat 10. 2005; (200):1-203. View

Buist M, Cheng L, Yassi R, Bradshaw L, Richards W, Pullan A . An anatomical model of the gastric system for producing bioelectric and biomagnetic fields. Physiol Meas. 2004; 25(4):849-61. DOI: 10.1088/0967-3334/25/4/006. View

10.

Bradley C, Pullan A, Hunter P . Geometric modeling of the human torso using cubic hermite elements. Ann Biomed Eng. 1997; 25(1):96-111. DOI: 10.1007/BF02738542. View

11.

Henry J, OSullivan G, Pandit A . Using computed tomography scans to develop an ex-vivo gastric model. World J Gastroenterol. 2007; 13(9):1372-7. PMC: 4146921. DOI: 10.3748/wjg.v13.i9.1372. View

12.

Richards W, Bradshaw L, Staton D, Garrard C, Liu F, Buchanan S . Magnetoenterography (MENG): noninvasive measurement of bioelectric activity in human small intestine. Dig Dis Sci. 1996; 41(12):2293-301. DOI: 10.1007/BF02100117. View

13.

Bradshaw L, Ladipo J, Staton D, Wikswo Jr J, Richards W . The human vector magnetogastrogram and magnetoenterogram. IEEE Trans Biomed Eng. 1999; 46(8):959-70. DOI: 10.1109/10.775406. View

14.

Buist M, Sands G, Hunter P, Pullan A . A deformable finite element derived finite difference method for cardiac activation problems. Ann Biomed Eng. 2003; 31(5):577-88. DOI: 10.1114/1.1567283. View

15.

Irimia A, Cheng L, Buist M, Pullan A, Bradshaw L . An integrative software package for gastrointestinal biomagnetic data acquisition and analysis using SQUID magnetometers. Comput Methods Programs Biomed. 2006; 83(2):83-94. DOI: 10.1016/j.cmpb.2006.03.006. View

16.

Pullan A, Cheng L, Yassi R, Buist M . Modelling gastrointestinal bioelectric activity. Prog Biophys Mol Biol. 2004; 85(2-3):523-50. DOI: 10.1016/j.pbiomolbio.2004.02.003. View

17.

Bradshaw L, Myers A, Wikswo J, Richards W . A spatio-temporal dipole simulation of gastrointestinal magnetic fields. IEEE Trans Biomed Eng. 2003; 50(7):836-47. DOI: 10.1109/TBME.2003.813549. View