Temperature-sensitive Mutations at the Carboxy Terminus of the Alpha Subunit of the Escherichia Coli F1F0 ATP Synthase
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Mutations were constructed in the a subunit of the F1F0 ATP synthase from Escherichia coli. Truncated forms of this subunit showed a temperature sensitivity phenotype. We conclude that the carboxy terminus of the a subunit is not involved directly with proton translocation but that it has an important structural role.
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