The Importance of Left Ventricular Function for Long-term Outcome After Primary Percutaneous Coronary Intervention

Overview

Journal BMC Cardiovasc Disord

Publisher Biomed Central

Specialty Cardiology & Vascular Diseases

Date 2008 Feb 26

PMID 18294397

Citations 18

Authors

Pieter A van der Vleuten

Saman Rasoul

Willem Huurnink

Iwan Cc van der Horst

Riemer Hja Slart

Stoffer Reiffers

Rudi A Dierckx

Rene A Tio

Jan Paul Ottervanger

Menko-Jan de Boer

Felix Zijlstra

Affiliations

Soon will be listed here.

Abstract

Background: In the present study we sought to determine the long-term prognostic value of left ventricular ejection fraction (LVEF), assessed by planar radionuclide ventriculography (PRV), after ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PPCI).

Methods: In total 925 patients underwent PRV for LVEF assessment after PPCI for myocardial infarction before discharge from the hospital. PRV was performed with a standard dose of 500 Mbq of 99mTc-pertechnetate. Average follow-up time was 2.5 years.

Results: Mean (+/- SD) age was 60 +/- 12 years. Mean (+/- SD) LVEF was 45.7 +/- 12.2 %. 1 year survival was 97.3 % and 3 year survival was 94.2 %. Killip class, multi vessel-disease, previous cardiovascular events, peak creatin kinase and its MB fraction, age and LVEF proved to be univariate predictors of mortality. When entered in a forward conditional Cox regression model age and LVEF were independent predictors of 1 and 3 year mortality.

Conclusion: LVEF assessed by PRV is a powerful independent predictor of long term mortality after PPCI for STEMI.

Citing Articles

Myocardial injury and clinical outcome in octogenarians after non-ST-elevation myocardial infarction.

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PMID: 39105073 PMC: 11299492. DOI: 10.3389/fcvm.2024.1422878.

Prognostic Value of Preoperative Assessment of Left Ventricular Function in Patients Undergoing Percutaneous Coronary Intervention.

Yang M, Guo F, Yang Y, Jing Z, Sun K Rev Cardiovasc Med. 2024; 24(3):80.

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Shen J, Liu G, Yang Y, Li X, Zhu Y, Xiang Z Clin Res Cardiol. 2021; 110(9):1439-1449.

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Diagnostic accuracy of strain imaging in predicting myocardial viability after an ST-elevation myocardial infarction.

Mghaieth Zghal F, Boudiche S, Haboubi S, Neji H, Ben Halima M, Rekik B Medicine (Baltimore). 2020; 99(19):e19528.

PMID: 32384424 PMC: 7220414. DOI: 10.1097/MD.0000000000019528.

Combined value of left ventricular ejection fraction and the Model for End-Stage Liver Disease (MELD) score for predicting mortality in patients with acute coronary syndrome who were undergoing percutaneous coronary intervention.

Kiris T, Avci E, Celik A BMC Cardiovasc Disord. 2018; 18(1):44.

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