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Isolation and Characterization of New Cannabis Constituents from a High Potency Variety

Overview
Journal Planta Med
Specialty Biology
Date 2008 Feb 20
PMID 18283614
Citations 31
Authors
Mohamed M Radwan
Samir A Ross
Desmond Slade
Safwat A Ahmed
Fazila Zulfiqar
Mahmoud A ElSohly
Affiliations
Soon will be listed here.
Abstract

Phytochemical investigation of a high potency variety of Cannabis sativa L. resulted in the isolation of six new metabolites, (+/-)-6,7-trans-epoxycannabigerolic acid ( 2), (+/-)-6,7- CIS-epoxycannabigerolic acid ( 3), (+/-)-6,7- CIS-epoxycannabigerol ( 4), (+/-)-6,7-trans-epoxycannabigerol ( 5), 5'-methyl-4-pentylbiphenyl-2,2',6-triol ( 7), and 7-methoxycannabispirone ( 8), along with seven known compounds namely, cannabigerolic acid ( 1), 5'-methoxycannabigerolic acid ( 6), cannabispirone ( 9), beta-cannabispiranol ( 10), dehydrocannabifuran ( 11), cannflavin B ( 12) and cannabigerol ( 13). The antimicrobial as well as the antileishmanial activities were investigated.

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