Prevalence of and Risk Factors for Subclinical Cardiovascular Disease in Selected US Hispanic Ethnic Groups: the Multi-Ethnic Study of Atherosclerosis

Overview

Journal Am J Epidemiol

Publisher Oxford University Press

Specialty Public Health

Date 2008 Feb 20

PMID 18283034

Citations 57

Authors

Matthew A Allison

Matthew J Budoff

Nathan D Wong

Roger S Blumenthal

Pamela J Schreiner

Michael H Criqui

Affiliations

Soon will be listed here.

Abstract

In this study, the authors determined the prevalence and extent of cardiovascular disease (CVD) risk factors and subclinical CVD in four US Hispanic subgroups, as well as associations between the CVD risk factors and subclinical CVD in these groups. Participants were 1,437 Hispanic men and women enrolled in the Multi-Ethnic Study of Atherosclerosis in 2000-2002. Fifty-six percent were Mexican-American, 12% were Dominican-American, 14% were Puerto Rican-American, and 18% were Other Hispanic-American. All participants underwent clinical examinations for coronary artery calcium, thoracic aortic calcium, carotid intimal-medial thickness, ankle-brachial index, left ventricular mass, and left ventricular size. Mexican Americans had the highest levels of coronary artery calcium, thoracic aortic calcium, and carotid intimal-medial thickness, while Puerto Rican Americans had the highest prevalence of an ankle-brachial index less than 1.0 and levels of left ventricular mass. The magnitudes of the associations between coronary artery calcium and age, sex, and body mass index were similar across all Hispanic subgroups. However, there were differences in the magnitude and significance of the associations between coronary artery calcium and hypertension, hypercholesterolemia, and cigarette smoking among the different Hispanic subgroups. This finding was also present for the other subclinical CVD measures. These results suggest a differential relationship between risk factors and either prevalence or extent of subclinical disease by Hispanic subgroup.

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References

OLeary D, Polak J, WOLFSON Jr S, Bond M, BOMMER W, Sheth S . Use of sonography to evaluate carotid atherosclerosis in the elderly. The Cardiovascular Health Study. CHS Collaborative Research Group. Stroke. 1991; 22(9):1155-63. DOI: 10.1161/01.str.22.9.1155. View

Flegal K, Ezzati T, Harris M, Haynes S, Juarez R, Knowler W . Prevalence of diabetes in Mexican Americans, Cubans, and Puerto Ricans from the Hispanic Health and Nutrition Examination Survey, 1982-1984. Diabetes Care. 1991; 14(7):628-38. DOI: 10.2337/diacare.14.7.628. View

Bertoni A, Goff Jr D, DAgostino Jr R, Liu K, Hundley W, Lima J . Diabetic cardiomyopathy and subclinical cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA). Diabetes Care. 2006; 29(3):588-94. DOI: 10.2337/diacare.29.03.06.dc05-1501. View

FRIEDEWALD W, Levy R, Fredrickson D . Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972; 18(6):499-502. View

Espeland M, Evans G, Wagenknecht L, OLeary D, Zaccaro D, Crouse J . Site-specific progression of carotid artery intimal-medial thickness. Atherosclerosis. 2003; 171(1):137-43. DOI: 10.1016/j.atherosclerosis.2003.07.009. View

Mitchell B, Stern M, Haffner S, Hazuda H, PATTERSON J . Risk factors for cardiovascular mortality in Mexican Americans and non-Hispanic whites. San Antonio Heart Study. Am J Epidemiol. 1990; 131(3):423-33. DOI: 10.1093/oxfordjournals.aje.a115517. View

Reaven P, Thurmond D, Domb A, Gerkin R, Budoff M, Goldman S . Comparison of frequency of coronary artery calcium in healthy Hispanic versus non-Hispanic white men by electron beam computed tomography. Am J Cardiol. 2003; 92(10):1198-200. DOI: 10.1016/j.amjcard.2003.07.030. View

McDermott M, Greenland P, Liu K, Guralnik J, Celic L, Criqui M . The ankle brachial index is associated with leg function and physical activity: the Walking and Leg Circulation Study. Ann Intern Med. 2002; 136(12):873-83. DOI: 10.7326/0003-4819-136-12-200206180-00008. View

Chambless L, Heiss G, Folsom A, Rosamond W, Szklo M, Sharrett A . Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. Am J Epidemiol. 1997; 146(6):483-94. DOI: 10.1093/oxfordjournals.aje.a009302. View

10.

Lizarzaburu J, Palinkas L . Immigration, acculturation, and risk factors for obesity and cardiovascular disease: a comparison between Latinos of Peruvian descent in Peru and in the United States. Ethn Dis. 2002; 12(3):342-52. View

11.

Hazuda H, Haffner S, Stern M, Eifler C . Effects of acculturation and socioeconomic status on obesity and diabetes in Mexican Americans. The San Antonio Heart Study. Am J Epidemiol. 1988; 128(6):1289-301. DOI: 10.1093/oxfordjournals.aje.a115082. View

12.

Meigs J, Wilson P, Nathan D, DAgostino Sr R, Williams K, Haffner S . Prevalence and characteristics of the metabolic syndrome in the San Antonio Heart and Framingham Offspring Studies. Diabetes. 2003; 52(8):2160-7. DOI: 10.2337/diabetes.52.8.2160. View

13.

Khan L, Sobal J, Martorell R . Acculturation, socioeconomic status, and obesity in Mexican Americans, Cuban Americans, and Puerto Ricans. Int J Obes Relat Metab Disord. 1997; 21(2):91-6. DOI: 10.1038/sj.ijo.0800367. View

14.

Mensah G, Mokdad A, Ford E, Greenlund K, Croft J . State of disparities in cardiovascular health in the United States. Circulation. 2005; 111(10):1233-41. DOI: 10.1161/01.CIR.0000158136.76824.04. View

15.

Kondos G, Hoff J, Sevrukov A, Daviglus M, Garside D, Devries S . Electron-beam tomography coronary artery calcium and cardiac events: a 37-month follow-up of 5635 initially asymptomatic low- to intermediate-risk adults. Circulation. 2003; 107(20):2571-6. DOI: 10.1161/01.CIR.0000068341.61180.55. View

16.

Raggi P, Shaw L, Berman D, Callister T . Prognostic value of coronary artery calcium screening in subjects with and without diabetes. J Am Coll Cardiol. 2004; 43(9):1663-9. DOI: 10.1016/j.jacc.2003.09.068. View

17.

Bild D, Bluemke D, Burke G, Detrano R, Diez Roux A, Folsom A . Multi-Ethnic Study of Atherosclerosis: objectives and design. Am J Epidemiol. 2002; 156(9):871-81. DOI: 10.1093/aje/kwf113. View

18.

LINDEMAN R, Romero L, Hundley R, Allen A, Liang H, Baumgartner R . Prevalences of type 2 diabetes, the insulin resistance syndrome, and coronary heart disease in an elderly, biethnic population. Diabetes Care. 1998; 21(6):959-66. DOI: 10.2337/diacare.21.6.959. View

19.

Hodis H, Mack W, Labree L, Selzer R, Liu C, Liu C . The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med. 1998; 128(4):262-9. DOI: 10.7326/0003-4819-128-4-199802150-00002. View

20.

Agatston A, Janowitz W, HILDNER F, Zusmer N, VIAMONTE Jr M, Detrano R . Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990; 15(4):827-32. DOI: 10.1016/0735-1097(90)90282-t. View