Regulation of Membrane Trafficking in Polarized Epithelial Cells

Overview

Journal Curr Opin Cell Biol

Publisher Elsevier

Specialty Cell Biology

Date 2008 Feb 20

PMID 18282697

Citations 35

Authors

Heike Folsch

Affiliations

Soon will be listed here.

Abstract

Polarized epithelial cells continuously sort transmembrane proteins to either apical or basolateral plasma membrane domains. Research in recent years has made tremendous progress in understanding the molecular mechanisms of the major pathways to either basolateral or apical domain. This understanding will help us elucidating how these pathways are interconnected in ensuring maintenance of cell polarity and integrity of epithelial monolayers.

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References

Sahlender D, Roberts R, Arden S, Spudich G, Taylor M, Luzio J . Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis. J Cell Biol. 2005; 169(2):285-95. PMC: 2171882. DOI: 10.1083/jcb.200501162. View

Prigent M, Dubois T, Raposo G, Derrien V, Tenza D, Rosse C . ARF6 controls post-endocytic recycling through its downstream exocyst complex effector. J Cell Biol. 2003; 163(5):1111-21. PMC: 2173613. DOI: 10.1083/jcb.200305029. View

Folsch H . The building blocks for basolateral vesicles in polarized epithelial cells. Trends Cell Biol. 2005; 15(4):222-8. DOI: 10.1016/j.tcb.2005.02.006. View

Yoshimura S, Egerer J, Fuchs E, Haas A, Barr F . Functional dissection of Rab GTPases involved in primary cilium formation. J Cell Biol. 2007; 178(3):363-9. PMC: 2064854. DOI: 10.1083/jcb.200703047. View

Lafont F, Burkhardt J, Simons K . Involvement of microtubule motors in basolateral and apical transport in kidney cells. Nature. 1994; 372(6508):801-3. DOI: 10.1038/372801a0. View

Moskalenko S, Henry D, Rosse C, Mirey G, Camonis J, White M . The exocyst is a Ral effector complex. Nat Cell Biol. 2001; 4(1):66-72. DOI: 10.1038/ncb728. View

Simmen T, Honing S, Icking A, Tikkanen R, Hunziker W . AP-4 binds basolateral signals and participates in basolateral sorting in epithelial MDCK cells. Nat Cell Biol. 2002; 4(2):154-9. DOI: 10.1038/ncb745. View

Noda Y, Okada Y, Saito N, Setou M, Xu Y, Zhang Z . KIFC3, a microtubule minus end-directed motor for the apical transport of annexin XIIIb-associated Triton-insoluble membranes. J Cell Biol. 2001; 155(1):77-88. PMC: 2150803. DOI: 10.1083/jcb.200108042. View

Lafont F, Lecat S, Verkade P, Simons K . Annexin XIIIb associates with lipid microdomains to function in apical delivery. J Cell Biol. 1998; 142(6):1413-27. PMC: 2141766. DOI: 10.1083/jcb.142.6.1413. View

10.

Janvier K, Kato Y, Boehm M, Rose J, Martina J, Kim B . Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes. J Cell Biol. 2003; 163(6):1281-90. PMC: 2173715. DOI: 10.1083/jcb.200307157. View

11.

Grindstaff K, Yeaman C, Anandasabapathy N, Hsu S, Rodriguez-Boulan E, Scheller R . Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. Cell. 1998; 93(5):731-40. DOI: 10.1016/s0092-8674(00)81435-x. View

12.

Nakagawa T, Setou M, Seog D, Ogasawara K, Dohmae N, Takio K . A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex. Cell. 2000; 103(4):569-81. DOI: 10.1016/s0092-8674(00)00161-6. View

13.

Munson M, Novick P . The exocyst defrocked, a framework of rods revealed. Nat Struct Mol Biol. 2006; 13(7):577-81. DOI: 10.1038/nsmb1097. View

14.

Vieira O, Gaus K, Verkade P, Fullekrug J, Vaz W, Simons K . FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells. Proc Natl Acad Sci U S A. 2006; 103(49):18556-61. PMC: 1693701. DOI: 10.1073/pnas.0608291103. View

15.

Delacour D, Cramm-Behrens C, Drobecq H, Le Bivic A, Naim H, Jacob R . Requirement for galectin-3 in apical protein sorting. Curr Biol. 2006; 16(4):408-14. DOI: 10.1016/j.cub.2005.12.046. View

16.

Ohno H, Tomemori T, Nakatsu F, Okazaki Y, Aguilar R, Foelsch H . Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells. FEBS Lett. 1999; 449(2-3):215-20. DOI: 10.1016/s0014-5793(99)00432-9. View

17.

Pocard T, Le Bivic A, Galli T, Zurzolo C . Distinct v-SNAREs regulate direct and indirect apical delivery in polarized epithelial cells. J Cell Sci. 2007; 120(Pt 18):3309-20. DOI: 10.1242/jcs.007948. View

18.

GALLI T, Zahraoui A, Vaidyanathan V, Raposo G, Tian J, Karin M . A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells. Mol Biol Cell. 1998; 9(6):1437-48. PMC: 25366. DOI: 10.1091/mbc.9.6.1437. View

19.

Folsch H, Pypaert M, Schu P, Mellman I . Distribution and function of AP-1 clathrin adaptor complexes in polarized epithelial cells. J Cell Biol. 2001; 152(3):595-606. PMC: 2195989. DOI: 10.1083/jcb.152.3.595. View

20.

Sfakianos J, Togawa A, Maday S, Hull M, Pypaert M, Cantley L . Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells. J Cell Biol. 2007; 179(6):1133-40. PMC: 2140027. DOI: 10.1083/jcb.200709111. View