Are Cancer and Ageing Different Sides of the Same Coin? Conference on Cancer and Ageing

Overview

Journal EMBO Rep

Specialty Molecular Biology

Date 2008 Feb 9

PMID 18259218

Citations 6

Authors

Graham Pawelec

Rafael Solana

Affiliations

Soon will be listed here.

Citing Articles

Ribose-5-phosphate isomerase A overexpression promotes liver cancer development in transgenic zebrafish via activation of ERK and β-catenin pathways.

Chou Y, Chen L, Tsai S, Tu H, Lu J, Ciou S Carcinogenesis. 2018; 40(3):461-473.

PMID: 30418535 PMC: 6514454. DOI: 10.1093/carcin/bgy155.

Natural killer cell immunosenescence in acute myeloid leukaemia patients: new targets for immunotherapeutic strategies?.

Sanchez-Correa B, Campos C, Pera A, Bergua J, Arcos M, Banas H Cancer Immunol Immunother. 2015; 65(4):453-63.

PMID: 26059279 PMC: 11029066. DOI: 10.1007/s00262-015-1720-6.

Human NK cells in acute myeloid leukaemia patients: analysis of NK cell-activating receptors and their ligands.

Sanchez-Correa B, Morgado S, Gayoso I, Bergua J, G Casado J, Arcos M Cancer Immunol Immunother. 2011; 60(8):1195-205.

PMID: 21644031 PMC: 11028638. DOI: 10.1007/s00262-011-1050-2.

Age-dependent association between low frequency of CD27/CD28 expression on pp65 CD8+ T cells and cytomegalovirus replication after transplantation.

Cantisan S, Torre-Cisneros J, Lara R, Rodriguez-Benot A, Santos F, Gutierrez-Aroca J Clin Vaccine Immunol. 2009; 16(10):1429-38.

PMID: 19656991 PMC: 2756845. DOI: 10.1128/CVI.00214-09.

Ageing, oxidative stress and cancer: paradigms in parallax.

Benz C, Yau C Nat Rev Cancer. 2008; 8(11):875-9.

PMID: 18948997 PMC: 2603471. DOI: 10.1038/nrc2522.

References

Doubrovina E, Doubrovin M, Vider E, Sisson R, OReilly R, Dupont B . Evasion from NK cell immunity by MHC class I chain-related molecules expressing colon adenocarcinoma. J Immunol. 2003; 171(12):6891-9. DOI: 10.4049/jimmunol.171.12.6891. View

Kendall S, Adam S, Counter C . Genetically engineered human cancer models utilizing mammalian transgene expression. Cell Cycle. 2006; 5(10):1074-9. DOI: 10.4161/cc.5.10.2734. View

von Zglinicki T, Saretzki G, Docke W, Lotze C . Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence?. Exp Cell Res. 1995; 220(1):186-93. DOI: 10.1006/excr.1995.1305. View

Pawelec G, Koch S, Griesemann H, Rehbein A, Hahnel K, Gouttefangeas C . Immunosenescence, suppression and tumour progression. Cancer Immunol Immunother. 2005; 55(8):981-6. PMC: 11030987. DOI: 10.1007/s00262-005-0109-3. View

Effros R, Pawelec G . Replicative senescence of T cells: does the Hayflick Limit lead to immune exhaustion?. Immunol Today. 1997; 18(9):450-4. DOI: 10.1016/s0167-5699(97)01079-7. View

Pinkston-Gosse J, Kenyon C . DAF-16/FOXO targets genes that regulate tumor growth in Caenorhabditis elegans. Nat Genet. 2007; 39(11):1403-9. DOI: 10.1038/ng.2007.1. View

Apetoh L, Ghiringhelli F, Tesniere A, Obeid M, Ortiz C, Criollo A . Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med. 2007; 13(9):1050-9. DOI: 10.1038/nm1622. View

Solana R, Pawelec G, Tarazona R . Aging and innate immunity. Immunity. 2006; 24(5):491-4. DOI: 10.1016/j.immuni.2006.05.003. View

Aw D, Silva A, Palmer D . Immunosenescence: emerging challenges for an ageing population. Immunology. 2007; 120(4):435-46. PMC: 2265901. DOI: 10.1111/j.1365-2567.2007.02555.x. View

10.

Francis R, Barton M, Kimble J, Schedl T . gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics. 1995; 139(2):579-606. PMC: 1206368. DOI: 10.1093/genetics/139.2.579. View

11.

Solana R, G Casado J, Delgado E, DelaRosa O, Marin J, Duran E . Lymphocyte activation in response to melanoma: interaction of NK-associated receptors and their ligands. Cancer Immunol Immunother. 2006; 56(1):101-9. PMC: 11030256. DOI: 10.1007/s00262-006-0141-y. View

12.

Giorgio M, Trinei M, Migliaccio E, Pelicci P . Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals?. Nat Rev Mol Cell Biol. 2007; 8(9):722-8. DOI: 10.1038/nrm2240. View

13.

de Visser K, Coussens L . The interplay between innate and adaptive immunity regulates cancer development. Cancer Immunol Immunother. 2005; 54(11):1143-52. PMC: 11032791. DOI: 10.1007/s00262-005-0702-5. View

14.

Tyner S, Venkatachalam S, Choi J, Jones S, Ghebranious N, Igelmann H . p53 mutant mice that display early ageing-associated phenotypes. Nature. 2002; 415(6867):45-53. DOI: 10.1038/415045a. View