Malignant Fibrous Histiocytoma Associated with Bone Infarcts: Report of a Case

Overview

Journal Clin Orthop Relat Res

Publisher Wolters Kluwer

Specialty Orthopedics

Date 1976 Jul 1

PMID 182426

Citations 12

Authors

R H Michael

H D Dorfman

Affiliations

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Abstract

A caisson worker with symmetrical bone infarcts in the tibiae demonstrated a malignant transformation of one of the bone infarcts with wide-spread metastases to the lungs and viscera. Histologically, the tumor was found to be a malignant fibrous histiocytoma and despite amputation, the patient died approximately one year following the diagnosis. This case lends credence to the concept of a cause and effect relationship existing between bone infarcts and the subsequent development of bone sarcoma.

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