Rule-selection and Action-selection Have a Shared Neuroanatomical Basis in the Human Prefrontal and Parietal Cortex

Overview

Journal Cereb Cortex

Publisher Oxford University Press

Specialty Neurology

Date 2008 Feb 1

PMID 18234684

Citations 27

Authors

J Rowe

L Hughes

D Eckstein

A M Owen

Affiliations

Soon will be listed here.

Abstract

The human capacity for voluntary action is one of the major contributors to our success as a species. In addition to choosing actions themselves, we can also voluntarily choose behavioral codes or sets of rules that can guide future responses to events. Such rules have been proposed to be superordinate to actions in a cognitive hierarchy and mediated by distinct brain regions. We used event-related functional magnetic resonance imaging to study novel tasks of rule-based and voluntary action. We show that the voluntary selection of rules to govern future responses to events is associated with activation of similar regions of prefrontal and parietal cortex as the voluntary selection of an action itself. The results are discussed in terms of hierarchical models and the adaptive coding potential of prefrontal neurons and their contribution to a global workspace for nonautomatic tasks. These tasks include the choices we make about our behavior.

Citing Articles

Alterations of Regional Homogeneity in Children With Congenital Sensorineural Hearing Loss: A Resting-State fMRI Study.

Guo P, Lang S, Jiang M, Wang Y, Zeng Z, Wen Z Front Neurosci. 2021; 15:678910.

PMID: 34690668 PMC: 8526795. DOI: 10.3389/fnins.2021.678910.

Functional localization and categorization of intentional decisions in humans: A meta-analysis of brain imaging studies.

Si R, Rowe J, Zhang J Neuroimage. 2021; 242:118468.

PMID: 34390878 PMC: 8463837. DOI: 10.1016/j.neuroimage.2021.118468.

Feature-specific neural reactivation during episodic memory.

Bone M, Ahmad F, Buchsbaum B Nat Commun. 2020; 11(1):1945.

PMID: 32327642 PMC: 7181630. DOI: 10.1038/s41467-020-15763-2.

Outcome contingency selectively affects the neural coding of outcomes but not of tasks.

Wisniewski D, Forstmann B, Brass M Sci Rep. 2019; 9(1):19395.

PMID: 31852993 PMC: 6920387. DOI: 10.1038/s41598-019-55887-0.

Looking up while reaching out: the neural correlates of making eye and arm movements in different spatial planes.

Gorbet D, Sergio L Exp Brain Res. 2018; 237(1):57-70.

PMID: 30306244 DOI: 10.1007/s00221-018-5395-z.

References

Jenkins I, Jahanshahi M, Jueptner M, Passingham R, Brooks D . Self-initiated versus externally triggered movements. II. The effect of movement predictability on regional cerebral blood flow. Brain. 2000; 123 ( Pt 6):1216-28. DOI: 10.1093/brain/123.6.1216. View

Jueptner M, Jenkins I, Brooks D, Frackowiak R, Passingham R . The sensory guidance of movement: a comparison of the cerebellum and basal ganglia. Exp Brain Res. 1996; 112(3):462-74. DOI: 10.1007/BF00227952. View

Wallis J, Anderson K, Miller E . Single neurons in prefrontal cortex encode abstract rules. Nature. 2001; 411(6840):953-6. DOI: 10.1038/35082081. View

Freedman D, Riesenhuber M, Poggio T, Miller E . Categorical representation of visual stimuli in the primate prefrontal cortex. Science. 2001; 291(5502):312-6. DOI: 10.1126/science.291.5502.312. View

Miller E, Cohen J . An integrative theory of prefrontal cortex function. Annu Rev Neurosci. 2001; 24:167-202. DOI: 10.1146/annurev.neuro.24.1.167. View

Thirion B, Pinel P, Meriaux S, Roche A, Dehaene S, Poline J . Analysis of a large fMRI cohort: Statistical and methodological issues for group analyses. Neuroimage. 2007; 35(1):105-20. DOI: 10.1016/j.neuroimage.2006.11.054. View

Amunts K, Weiss P, Mohlberg H, Pieperhoff P, Eickhoff S, Gurd J . Analysis of neural mechanisms underlying verbal fluency in cytoarchitectonically defined stereotaxic space--the roles of Brodmann areas 44 and 45. Neuroimage. 2004; 22(1):42-56. DOI: 10.1016/j.neuroimage.2003.12.031. View

Rushworth M, Hadland K, Paus T, Sipila P . Role of the human medial frontal cortex in task switching: a combined fMRI and TMS study. J Neurophysiol. 2002; 87(5):2577-92. DOI: 10.1152/jn.2002.87.5.2577. View

Sakai K, Passingham R . Prefrontal set activity predicts rule-specific neural processing during subsequent cognitive performance. J Neurosci. 2006; 26(4):1211-8. PMC: 6674561. DOI: 10.1523/JNEUROSCI.3887-05.2006. View

10.

Dehaene S, Kerszberg M, Changeux J . A neuronal model of a global workspace in effortful cognitive tasks. Proc Natl Acad Sci U S A. 1998; 95(24):14529-34. PMC: 24407. DOI: 10.1073/pnas.95.24.14529. View

11.

Spence S, Hirsch S, Brooks D, Grasby P . Prefrontal cortex activity in people with schizophrenia and control subjects. Evidence from positron emission tomography for remission of 'hypofrontality' with recovery from acute schizophrenia. Br J Psychiatry. 1998; 172:316-23. DOI: 10.1192/bjp.172.4.316. View

12.

Haynes J, Sakai K, Rees G, Gilbert S, Frith C, Passingham R . Reading hidden intentions in the human brain. Curr Biol. 2007; 17(4):323-8. DOI: 10.1016/j.cub.2006.11.072. View

13.

Brefczynski J, Deyoe E . A physiological correlate of the 'spotlight' of visual attention. Nat Neurosci. 1999; 2(4):370-4. DOI: 10.1038/7280. View

14.

Chafee M, Goldman-Rakic P . Matching patterns of activity in primate prefrontal area 8a and parietal area 7ip neurons during a spatial working memory task. J Neurophysiol. 1998; 79(6):2919-40. DOI: 10.1152/jn.1998.79.6.2919. View

15.

Rushworth M, Hadland K, Gaffan D, Passingham R . The effect of cingulate cortex lesions on task switching and working memory. J Cogn Neurosci. 2003; 15(3):338-53. DOI: 10.1162/089892903321593072. View

16.

Ridderinkhof K, Ullsperger M, Crone E, Nieuwenhuis S . The role of the medial frontal cortex in cognitive control. Science. 2004; 306(5695):443-7. DOI: 10.1126/science.1100301. View

17.

Nieder A, Miller E . A parieto-frontal network for visual numerical information in the monkey. Proc Natl Acad Sci U S A. 2004; 101(19):7457-62. PMC: 409940. DOI: 10.1073/pnas.0402239101. View

18.

Donohue S, Wendelken C, Crone E, Bunge S . Retrieving rules for behavior from long-term memory. Neuroimage. 2005; 26(4):1140-9. DOI: 10.1016/j.neuroimage.2005.03.019. View

19.

Murphy K, Garavan H . An empirical investigation into the number of subjects required for an event-related fMRI study. Neuroimage. 2004; 22(2):879-85. DOI: 10.1016/j.neuroimage.2004.02.005. View

20.

Wiese H, Stude P, Nebel K, de Greiff A, Forsting M, Diener H . Movement preparation in self-initiated versus externally triggered movements: an event-related fMRI-study. Neurosci Lett. 2004; 371(2-3):220-5. DOI: 10.1016/j.neulet.2004.08.078. View