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Medical Decision Analysis in Infectious Diseases

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Date 2007 Dec 27
PMID 18159308
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Abstract

Medical decision analysis (MDA) has played an important role in assisting infectious disease physicians make decisions associated with varying levels of complexity. Clinicians are often uncomfortable with some aspects of MDA, particularly when utilities are used as outcome measures. However, as the present paper outlines, MDA may use other outcome variables, including costs and disease complications. In this context, this explicit, reproducible analytic framework is an important tool in the area of infectious diseases, and is frequently applied to many situations, including cost effectiveness analyses, studies involving assessment of risks versus benefits of preventive and treatment strategies, and other situations. The objective of this paper is to assist infectious diseases clinicians to understand better the role of MDA in clinical practice. In this regard, the principles of MDA are reviewed and a common clinical example is used for illustrative purposes.

References
1.
. Update: provisional Public Health Service recommendations for chemoprophylaxis after occupational exposure to HIV. MMWR Morb Mortal Wkly Rep. 1996; 45(22):468-80. View

2.
Magid D, Schwartz B, Craft J, Schwartz J . Prevention of Lyme disease after tick bites. A cost-effectiveness analysis. N Engl J Med. 1992; 327(8):534-41. DOI: 10.1056/NEJM199208203270806. View

3.
Allen U, Guerriere M, Read S, Detsky A . Percutaneous injuries among health care workers. The real value of human immunodeficiency virus testing of 'donor' blood. Arch Intern Med. 1991; 151(10):2033-40. DOI: 10.1001/archinte.151.10.2033. View

4.
Plume S . Choices, chances, values. Ann Thorac Surg. 1992; 53(3):373. DOI: 10.1016/0003-4975(92)90253-z. View

5.
. Public Health Service statement on management of occupational exposure to human immunodeficiency virus, including considerations regarding zidovudine postexposure use. MMWR Recomm Rep. 1990; 39(RR-1):1-14. View