Pheochromocytoma: Cyclic Attacks of Hypertension Alternating with Hypotension

Overview

Journal Nat Clin Pract Cardiovasc Med

Specialty Cardiology & Vascular Diseases

Date 2007 Dec 21

PMID 18094673

Citations 14

Authors

Sergio L Kobal

Esther Paran

Aamer Jamali

Solly Mizrahi

Robert J Siegel

Jonathan Leor

Affiliations

Soon will be listed here.

Abstract

Background: A 52-year-old woman was admitted to hospital with recurrent episodes of chest and abdominal pain, dyspnea, palpitations and diaphoresis. Continuous blood pressure recordings revealed rhythmic alternation between episodes of severe hypertension and episodes of hypotension. This cyclic hemodynamic crisis continued for 2 hours, with each cycle lasting around 15 min.

Investigations: Physical examination, electrocardiography, chest radiography, continuous intra-arterial pressure monitoring, blood and urine analysis, echocardiography, abdominal CT and 131I miodobenzylguanidine scanning.

Diagnosis: Pheochromocytoma--a catecholamine secreting tumor.

Management: Intravenous phentolamine and fluids, oral doxazosin and surgical removal of the tumor.

Citing Articles

Rapid cyclic fluctuations in blood pressure during two surgeries associated with pheochromocytoma: a case report.

Watanabe T, Miyoshi H, Nakamura R, Otsuki S, Saeki N, Tsutsumi Y JA Clin Rep. 2022; 8(1):80.

PMID: 36195694 PMC: 9532498. DOI: 10.1186/s40981-022-00569-6.

Clinical characteristics and outcomes of pheochromocytoma crisis: a literature review of 200 cases.

Ando Y, Ono Y, Sano A, Fujita N, Ono S, Tanaka Y J Endocrinol Invest. 2022; 45(12):2313-2328.

PMID: 35857218 DOI: 10.1007/s40618-022-01868-6.

Chlorpromazine Efficiently Treats the Crisis of Pheochromocytoma: Four Case Reports and Literature Review.

Wang J, He Z, Yang Y, Yu B, Wang H, Ding H Front Cardiovasc Med. 2021; 8:762371.

PMID: 34881311 PMC: 8645834. DOI: 10.3389/fcvm.2021.762371.

Emergent transcatheter arterial embolization to control critical blood pressure fluctuation associated with hypercatecholaminemic crisis in a patient with an unruptured retroperitoneal paraganglioma.

Kariyasu T, Machida H, Nishina Y, Tambo M, Miyagawa S, Rakue T Radiol Case Rep. 2021; 16(8):2065-2071.

PMID: 34158896 PMC: 8203589. DOI: 10.1016/j.radcr.2021.05.018.

Pheochromocytoma crisis with cyclic fluctuation in blood pressure mimics acute coronary syndrome.

Kometani M, Yoneda T, Maeda Y, Oe M, Takeda Y, Higashitani T Endocrinol Diabetes Metab Case Rep. 2021; 2020.

PMID: 33434177 PMC: 7577022. DOI: 10.1530/EDM-20-0115.