The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond

Overview

Journal Mol Cell

Publisher Cell Press

Specialty Cell Biology

Date 2007 Dec 18

PMID 18082598

Citations 479

Authors

Tony Hunter

Affiliations

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Abstract

Crosstalk between different types of posttranslational modification is an emerging theme in eukaryotic biology. Particularly prominent are the multiple connections between phosphorylation and ubiquitination, which act either positively or negatively in both directions to regulate these processes.

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