The Impact of Race on Weight Loss After Roux-en-Y Gastric Bypass Surgery

Overview

Journal Obes Surg

Date 2007 Dec 18

PMID 18080726

Citations 21

Authors

Glenn Harvin

Mark Delegge

Donald A Garrow

Affiliations

Soon will be listed here.

Abstract

Background: Gastric bypass surgery for morbid obesity has dramatically increased in volume over the past decade. Caucasian patients have been noted previously to lose more weight after bariatric surgery than African-Americans patients. Data regarding predictors of maintaining weight loss after surgery are minimal. We sought to determine predictors of long-term weight loss after bariatric surgery.

Methods: Retrospective analysis using a multivariate logistic regression model of all patients undergoing Roux-en-Y gastric bypass surgery at the Medical University of South Carolina from May 1993 to December 2004 for whom 2 years of follow-up data was available. Our dependent variable was the percentage of weight lost from baseline, dichotomized at +/-35%. Our primary independent variable was race, defined as Caucasian, African-American, or other. Relevant covariates were added to the model to control for their potential effects on outcome.

Results: One hundred eleven patients (17 male/94 female; 85% Caucasian, mean age 44 years (range 18-68 years). In our model, Caucasian subjects (adjusted odds ratio [OR] = 7.60, 95% confidence intervals [95%CI] = 1.83-31.5) and late post surgical complications (adjusted OR = 2.67, 95%CI = 1.05-6.80) significantly predicted weight loss at 2 years, after controlling for relevant confounders. Other covariates did not significantly impact the model.

Conclusion: Race and late post surgical complications significantly impacted the percentage of weight loss at 2 years for patients undergoing Roux-en-Y gastric bypass surgery at our institution. Future research should be directed at determining potential genetic and/or social reasons for these differences.

Citing Articles

New Insights on the Association Between Socioeconomic Status and Weight Loss After Bariatric Surgery: a Systematic Review and Meta-analysis.

Melendez-Araujo M, Berber L, de Sousa K, Figueiredo A, Lamarca F, Said Dutra E Obes Surg. 2022; 32(11):3752-3770.

PMID: 36094628 DOI: 10.1007/s11695-022-06269-5.

Racial variation in baseline characteristics and wait times among patients undergoing bariatric surgery.

Shen M, Jiang S, Millis M, Bonner S, Bonham A, Finks J Surg Endosc. 2022; 37(1):564-570.

PMID: 35508664 PMC: 9633573. DOI: 10.1007/s00464-022-09292-w.

Development and validation of a scoring system for pre-surgical and early post-surgical prediction of bariatric surgery unsuccess at 2 years.

Bioletto F, Pellegrini M, DEusebio C, Boschetti S, Rahimi F, De Francesco A Sci Rep. 2021; 11(1):21067.

PMID: 34702864 PMC: 8548411. DOI: 10.1038/s41598-021-00475-4.

Characteristics and resolution of hypertension in obese African American bariatric cohort.

Gandotra C, Basam M, Mahajan A, Ngwa J, Ortega G, Tran D Sci Rep. 2021; 11(1):1683.

PMID: 33462353 PMC: 7814052. DOI: 10.1038/s41598-021-81360-y.

Racial Comparisons of Postoperative Weight Loss and Eating-Disorder Psychopathology Among Patients Following Sleeve Gastrectomy Surgery.

Ivezaj V, Fu E, Lydecker J, Duffy A, Grilo C Obesity (Silver Spring). 2019; 27(5):740-745.

PMID: 30925196 PMC: 6478551. DOI: 10.1002/oby.22446.

References

Lara M, Kothari S, Sugerman H . Surgical management of obesity: a review of the evidence relating to the health benefits and risks. Treat Endocrinol. 2005; 4(1):55-64. DOI: 10.2165/00024677-200504010-00006. View

Madan A, Tichansky D, Coday M, Fain J . Comparison of IL-8, IL-6 and PGE(2) formation by visceral (omental) adipose tissue of obese Caucasian compared to African-American women. Obes Surg. 2006; 16(10):1342-50. DOI: 10.1381/096089206778663652. View

White M, ONeil P, Kolotkin R, Byrne T . Gender, race, and obesity-related quality of life at extreme levels of obesity. Obes Res. 2004; 12(6):949-55. DOI: 10.1038/oby.2004.116. View

Hsu L, Benotti P, Dwyer J, Roberts S, Saltzman E, Shikora S . Nonsurgical factors that influence the outcome of bariatric surgery: a review. Psychosom Med. 1998; 60(3):338-46. DOI: 10.1097/00006842-199805000-00021. View

Benotti P, Forse R . The role of gastric surgery in the multidisciplinary management of severe obesity. Am J Surg. 1995; 169(3):361-7. DOI: 10.1016/s0002-9610(99)80177-9. View

Mason E, Tang S, Renquist K, Barnes D, Cullen J, Doherty C . A decade of change in obesity surgery. National Bariatric Surgery Registry (NBSR) Contributors. Obes Surg. 1997; 7(3):189-97. DOI: 10.1381/096089297765555719. View

. Proceedings of the ASBS Consensus Conference on the State of Bariatric Surgery and Morbid Obesity: Health Implications for Patients, Health Professionals and Third-Party Payers, Washington, DC, USA, May 6-7, 2004. Surg Obes Relat Dis. 2006; 1(2):105-53. DOI: 10.1016/j.soard.2005.01.006. View

Morland K, Wing S, Roux A, Poole C . Neighborhood characteristics associated with the location of food stores and food service places. Am J Prev Med. 2002; 22(1):23-9. DOI: 10.1016/s0749-3797(01)00403-2. View

Zenk S, Schulz A, Israel B, James S, Bao S, Wilson M . Neighborhood racial composition, neighborhood poverty, and the spatial accessibility of supermarkets in metropolitan Detroit. Am J Public Health. 2005; 95(4):660-7. PMC: 1449238. DOI: 10.2105/AJPH.2004.042150. View

10.

Buchwald H, Avidor Y, Braunwald E, Jensen M, Pories W, Fahrbach K . Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004; 292(14):1724-37. DOI: 10.1001/jama.292.14.1724. View

11.

Morland K, Wing S, Roux A . The contextual effect of the local food environment on residents' diets: the atherosclerosis risk in communities study. Am J Public Health. 2002; 92(11):1761-7. PMC: 1447325. DOI: 10.2105/ajph.92.11.1761. View

12.

. Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health. Obes Res. 1998; 6 Suppl 2:51S-209S. View

13.

Herpertz S, Kielmann R, WOLF A, Hebebrand J, Senf W . Do psychosocial variables predict weight loss or mental health after obesity surgery? A systematic review. Obes Res. 2004; 12(10):1554-69. DOI: 10.1038/oby.2004.195. View

14.

Buffington C, Marema R . Ethnic differences in obesity and surgical weight loss between African-American and Caucasian females. Obes Surg. 2006; 16(2):159-65. DOI: 10.1381/096089206775565258. View

15.

Nothwehr F . Attitudes and behaviors related to weight control in two diverse populations. Prev Med. 2004; 39(4):674-80. DOI: 10.1016/j.ypmed.2004.02.034. View

16.

Parikh M, Lo H, Chang C, Collings D, Fielding G, Ren C . Comparison of outcomes after laparoscopic adjustable gastric banding in African-Americans and whites. Surg Obes Relat Dis. 2006; 2(6):607-10. DOI: 10.1016/j.soard.2006.08.012. View

17.

Block J, Scribner R, DeSalvo K . Fast food, race/ethnicity, and income: a geographic analysis. Am J Prev Med. 2004; 27(3):211-7. DOI: 10.1016/j.amepre.2004.06.007. View

18.

Latner J, Wetzler S, Goodman E, Glinski J . Gastric bypass in a low-income, inner-city population: eating disturbances and weight loss. Obes Res. 2004; 12(6):956-61. DOI: 10.1038/oby.2004.117. View

19.

Martin L, Tan T, Holmes P, Becker D, Horn J, Mann L . Preoperative insurance status influences postoperative complication rates for gastric bypass. Am J Surg. 1991; 161(6):625-34. DOI: 10.1016/0002-9610(91)91244-d. View

20.

Kumanyika S, Wilson J . Weight-related attitudes and behaviors of black women. J Am Diet Assoc. 1993; 93(4):416-22. DOI: 10.1016/0002-8223(93)92287-8. View