Thoracoscopic Removal of Mediastinal Hyperfunctioning Parathyroid Glands: Personal Experience and Review of the Literature

Overview

Journal World J Surg

Publisher Wiley

Specialty General Surgery

Date 2007 Dec 8

PMID 18064517

Citations 29

Authors

P F Alesina

D Moka

J Mahlstedt

M K Walz

Affiliations

Soon will be listed here.

Abstract

Background: The presence of a mediastinal hyperfunctioning parathyroid gland is a rare condition that occurs in about 1% to 2% of cases. We present our experience with video-endoscopic parathyroidectomy and a review of the literature.

Methods: In seven patients (four male, three female; age 28-67 years) mediastinal hyperfunctioning parathyroid glands were removed by the thoracoscopic route (VATS). Six patients suffered from primary hyperpathyroidism and one woman from recurrent secondary hyperparathyroidism. Additionally, articles concerning endoscopic treatment of mediastinal parathyroid glands were collected from the medical databases. A total of 58 patients were found in the English and French literature.

Results: Neither intraoperative nor postoperative complications occurred in our patients. Operating time was 90 minutes (range 40-180 minutes). After a mean follow-up of 29+/-12 months (range 3-64), all patients are biochemically cured. The cases in the literature showed healing in 57 of 58 cases. Their mean operating time was 112 minutes (range 40-240 minutes). One perioperative death due to myocardial infarction and a major complications rate of 7% are described.

Conclusion: The thoracoscopic approach to mediastinal parathyroidectomy is a safe, feasible technique with a low complication rate and good cosmetic outcome. It should become the standard surgical access for mediastinal hyperfunctioning parathyroid glands.

Citing Articles

Robotic transthoracic approach to ectopic mediastinal parathyroid adenoma: A case report.

Dowling G, Hehir C, Daly G, Shuhaibar M, Walshe P Int J Surg Case Rep. 2024; 126():110719.

PMID: 39733582 PMC: 11743912. DOI: 10.1016/j.ijscr.2024.110719.

Giant Parathyroid Adenoma of the Posterior Mediastinum.

Jagminas R, Jociene J, Maskoliunaite V, Jagelavicius Z Medicina (Kaunas). 2024; 60(10).

PMID: 39459453 PMC: 11509815. DOI: 10.3390/medicina60101666.

A Surgical Management of Mediastinal Parathyroid Adenoma: A Regional Experience in Malaysia.

Tay Y, Balasubbiah N, Awang R, Retna Pandian B, Sathiamurthy N Cureus. 2024; 16(3):e56792.

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A case of mediastinal hyperparathyromatosis.

Spillane C, Calpin G, Singh S, OReilly K, Hehir C, Hill A J Surg Case Rep. 2024; 2024(1):rjad735.

PMID: 38250132 PMC: 10799250. DOI: 10.1093/jscr/rjad735.

Slipped capital femoral epiphysis as primary presentation in an adolescent with primary hyperparathyroidism due to ectopic mediastinal parathyroid adenoma.

Badhe P, Patil S, Vikram Reddy G, Sheshadri H, Jain S, Nikumbh T Clin Case Rep. 2023; 11(6):e7498.

PMID: 37361665 PMC: 10288011. DOI: 10.1002/ccr3.7498.

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