The Mx GTPase Family of Interferon-induced Antiviral Proteins

Overview

Journal Microbes Infect

Publisher Elsevier

Specialties Allergy & Immunology
Microbiology

Date 2007 Dec 8

PMID 18062906

Citations 82

Authors

Otto Haller

Silke Stertz

Georg Kochs

Affiliations

Soon will be listed here.

Abstract

Mx proteins are interferon-induced members of the dynamin superfamily of large GTPases. They inhibit a wide range of viruses by blocking an early stage of the replication cycle. Studies in genetically defined mouse strains highlight their powerful action in early antiviral host defence.

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