Characterization of CD34+ Cells from Canine Umbilical Cord Blood, Bone Marrow Leukocytes, and Peripheral Blood by Flow Cytometric Analysis
Overview
Authors
Affiliations
Characterization of CD34+ cells in canine bone marrow, umbilical cord blood, and peripheral blood was performed by flow cytometric analysis. The ratio of CD34+CD45hi cells, which are absent in human blood, was high in the CD34+ cell fraction, but 98% of these was suggested B-cells. The remaining CD34+CD45lo cells may comprise canine hematopoietic progenitor cells, and these cells accounted for 0.23 +/- 0.07% of the fraction in cord blood, 0.30 +/- 0.07% in bone marrow, and 0.02 +/- 0.01% in peripheral blood.
CD34 Protein: Its expression and function in inflammation.
Rodrigues C, Moga S, Singh B, Aulakh G Cell Tissue Res. 2023; 393(3):443-454.
PMID: 37450038 DOI: 10.1007/s00441-023-03811-4.
Ayabe T, Hisasue M, Yamada Y, Nitta S, Kikuchi K, Neo S Front Vet Sci. 2022; 9:936623.
PMID: 36172613 PMC: 9510753. DOI: 10.3389/fvets.2022.936623.
CD34 protein is expressed in murine, canine, and porcine lungs.
Aulakh G, Maltare S, Khanh L, Singh B Can J Vet Res. 2021; 85(3):161-169.
PMID: 34248259 PMC: 8243798.
A preclinical model of double- versus single-unit unrelated cord blood transplantation.
Georges G, Lesnikov V, Baran S, Aragon A, Lesnikova M, Jordan R Biol Blood Marrow Transplant. 2010; 16(8):1090-8.
PMID: 20304085 PMC: 2897972. DOI: 10.1016/j.bbmt.2010.03.010.