Fast and Robust Analysis of Dynamic Contrast Enhanced MRI Datasets

Overview

Journal Med Image Comput Comput Assist Interv

Publisher Springer

Date 2007 Nov 30

PMID 18044577

Citations 8

Authors

Olga Kubassova

Mikael Boesen

Roger D Boyle

Marco A Cimmino

Karl E Jensen

Henning Bliddal

Alexandra Radjenovic

Affiliations

Soon will be listed here.

Abstract

A fully automated method for quantitative analysis of dynamic contrast-enhanced MRI data acquired with low and high field scanners, using spin echo and gradient echo sequences, depicting various joints is presented. The method incorporates efficient pre-processing techniques and a robust algorithm for quantitative assessment of dynamic signal intensity vs. time curves. It provides differentiated information to the reader regarding areas with the most active perfusion and permits depiction of different disease activity in separate compartments of a joint. Additionally, it provides information on the speed of contrast agent uptake by various tissues. The method delivers objective and easily reproducible results, which have been favourably viewed by a number of medical experts.

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