Translation in Vitro of Vesicular Stomatitis Virus MRNA Lacking 5'-terminal 7-methylguanosine

Overview

Journal Nature

Specialty Science

Date 1976 Jul 1

PMID 180425

Citations 35

Authors

J K Rose

H F Lodish

Affiliations

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Abstract

The 5'-terminus 7-methylguanosine of vesicular stomatitis virus mRNA is not essential for translation of the mRNA. The 7-methylguanosine seems to have a mediating rather than an obligatory role in ribosome binding by the mRNA and in mRNA translation.

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