Identification of Streptococcus Uberis Multilocus Sequence Types Highly Associated with Mastitis

Overview

Journal Appl Environ Microbiol

Specialties Environmental Health
Microbiology

Date 2007 Nov 21

PMID 18024686

Citations 17

Authors

Takehiro Tomita

Brian Meehan

Nalin Wongkattiya

Jakob Malmo

Gillian Pullinger

James Leigh

Margaret Deighton

Affiliations

Soon will be listed here.

Abstract

Multilocus sequence typing analysis of Streptococcus uberis has identified a cluster of isolates associated with clinical and subclinical mastitis and a cluster associated with cows with low somatic cell counts in their milk. Specific groups of genotypes (global clonal complex [GCC] sequence type 5s [ST5s] and GCC ST143s) were highly associated (P = 0.006) with clinical and subclinical mastitis and may represent a lineage of virulent isolates, whereas isolates belonging to GCC ST86 were associated with low-cell-count cows. This study has, for the first time, demonstrated the occurrence of identical sequence types (ST60 and ST184) between different continents (Australasia and Europe) and different countries (Australia and New Zealand). The standardized index of association and the empirical estimation of the rate of recombination showed substantial recombination within the S. uberis population in Australia, consistent with previous multilocus sequence type analyses.

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