Electrochemical Behavior and Antioxidant and Prooxidant Activity of Natural Phenolics

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2007 Nov 6

PMID 17978760

Citations 60

Authors

Aleksandra Simic

Dragan Manojlovic

Dejan Segan

Marija Todorovic

Affiliations

Soon will be listed here.

Abstract

We have investigated the electrochemical oxidation of a number natural phenolics (salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values (>0.45) act as prooxidants.

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