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Variable Selection for Model-based High-dimensional Clustering and Its Application to Microarray Data

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Journal Biometrics
Specialty Public Health
Date 2007 Nov 1
PMID 17970821
Citations 26
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Abstract

Variable selection in high-dimensional clustering analysis is an important yet challenging problem. In this article, we propose two methods that simultaneously separate data points into similar clusters and select informative variables that contribute to the clustering. Our methods are in the framework of penalized model-based clustering. Unlike the classical L(1)-norm penalization, the penalty terms that we propose make use of the fact that parameters belonging to one variable should be treated as a natural "group." Numerical results indicate that the two new methods tend to remove noninformative variables more effectively and provide better clustering results than the L(1)-norm approach.

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