Obesity and the Polycystic Ovary Syndrome

Overview

Journal Med Clin North Am

Specialty General Medicine

Date 2007 Oct 30

PMID 17964914

Citations 8

Authors

Michael Magnotti

Walter Futterweit

Affiliations

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Abstract

Polycystic ovarian syndrome (PCOS) is extremely common among reproductive-aged women, but often goes undiagnosed. PCOS is associated with the metabolic syndrome and carries a greatly increased risk of impaired glucose tolerance and type 2 diabetes mellitus, and cardiovascular risks. Treatment of PCOS may provide relief of cosmetic problems and depression by improving patient self-esteem. In addition, because of its association with the metabolic syndrome, type 2 diabetes mellitus, and cardiovascular disease, its recognition and treatment can potentially be life saving. This article reviews the impact, pathophysiology, and associated risks of obesity and the metabolic syndrome in PCOS.

Citing Articles

Effect of High Fat Diet on Disease Development of Polycystic Ovary Syndrome and Lifestyle Intervention Strategies.

Han Y, Wu H, Sun S, Zhao R, Deng Y, Zeng S Nutrients. 2023; 15(9).

PMID: 37432488 PMC: 10180647. DOI: 10.3390/nu15092230.

The Visceral Adiposity Index (VAI) and Lipid Accumulation Product (LAP) Are Predictors of Insulin Resistance and Hyperandrogenaemia in Obesity/Overweight Women with Polycystic Ovary Syndrome.

Wang H, Cao H, Cao J, Zhang L Biomed Res Int. 2023; 2023:1508675.

PMID: 36814799 PMC: 9940946. DOI: 10.1155/2023/1508675.

Anti-Müllerian hormone was independently associated with central obesity but not with general obesity in women with PCOS.

Zeng X, Huang Y, Zhang M, Chen Y, Ye J, Han Y Endocr Connect. 2021; 11(1).

PMID: 34822342 PMC: 8789017. DOI: 10.1530/EC-21-0243.

Anthropometric and Biochemical Characteristics of Polycystic Ovarian Syndrome in South Indian Women Using AES-2006 Criteria.

Thathapudi S, Kodati V, Erukkambattu J, Katragadda A, Addepally U, Hasan Q Int J Endocrinol Metab. 2014; 12(1):e12470.

PMID: 24696694 PMC: 3968989. DOI: 10.5812/ijem.12470.

A case of successful treatment of comorbid obesity and polycystic ovarian disease with add-on metformin in bipolar disorder.

Agarwal S, Behere R, Venkatasubramanian G, Rao N, Varambally S, Gangadhar B Prim Care Companion CNS Disord. 2012; 13(5).

PMID: 22295263 PMC: 3267504. DOI: 10.4088/PCC.11l01164.