Spinal Brucellosis: a Review

Overview

Journal Skeletal Radiol

Specialties Orthopedics
Radiology

Date 2007 Oct 27

PMID 17962938

Citations 32

Authors

Mouna Chelli Bouaziz

Mohamed Fethi Ladeb

Mohamed Chakroun

Skander Chaabane

Affiliations

Soon will be listed here.

Abstract

Brucellosis is a zoonosis of worldwide distribution, relatively frequent in Mediterranean countries and in the Middle East. It is a systemic infection, caused by facultative intra-cellular bacteria of the genus Brucella, that can involve many organs and tissues. The spine is the most common site of musculoskeletal involvement, followed by the sacroiliac joints. The aim of this study was to assess the clinical, biological and imaging features of spinal brucellosis.

Citing Articles

Research hotspots and development trends of spondylitis in the past 30 years: a bibliometric analysis.

Wu J, Yuan H, Chen H Front Microbiol. 2025; 16:1541792.

PMID: 40046306 PMC: 11881824. DOI: 10.3389/fmicb.2025.1541792.

Chronic brucellosis with sacroiliitis: A case report.

Shrestha B, Shrestha P, Bastakoti S, Gupta P, Magar S Clin Case Rep. 2024; 12(11):e9525.

PMID: 39525808 PMC: 11548956. DOI: 10.1002/ccr3.9525.

Epidemiology and laboratory testing of Brucella spondylitis.

Lu Y, Qiu W, Zhang T, Cheng Q, Wang Y, Chen L Sci Rep. 2024; 14(1):26345.

PMID: 39487301 PMC: 11530653. DOI: 10.1038/s41598-024-77391-w.

MRI findings and classification of brucella spondylitis: a China multicenter study.

Gou L, Yang Y, Li J, Cai L, Xing W, Liu W Eur J Med Res. 2024; 29(1):469.

PMID: 39342400 PMC: 11438224. DOI: 10.1186/s40001-024-02011-2.

Imaging of Spondylodiscitis: A Comprehensive Updated Review-Multimodality Imaging Findings, Differential Diagnosis, and Specific Microorganisms Detection.

Crombe A, Fadli D, Clinca R, Reverchon G, Cevolani L, Girolami M Microorganisms. 2024; 12(5).

PMID: 38792723 PMC: 11123694. DOI: 10.3390/microorganisms12050893.

References

Ghozlan R, Boissy M, Caruel N . [Lumbar epiduritis disclosing brucellar spondylodiskitis]. Rev Rhum Mal Osteoartic. 1981; 48(1):60-3. View

Sharif H, Haddad M, Aabed M, Sammak B, Mutairi M . Imaging features of musculoskeletal brucellosis. Radiographics. 1994; 14(2):333-48. DOI: 10.1148/radiographics.14.2.8190957. View

Pourbagher A, Pourbagher M, Savas L, Turunc T, Demiroglu Y, Erol I . Epidemiologic, clinical, and imaging findings in brucellosis patients with osteoarticular involvement. AJR Am J Roentgenol. 2006; 187(4):873-80. DOI: 10.2214/AJR.05.1088. View

Sharif H, Aideyan O, Clark D, Madkour M, Aabed M, Mattsson T . Brucellar and tuberculous spondylitis: comparative imaging features. Radiology. 1989; 171(2):419-25. DOI: 10.1148/radiology.171.2.2704806. View

Zormpala A, Skopelitis E, Thanos L, Artinopoulos C, Kordossis T, Sipsas N . An unusual case of brucellar spondylitis involving both the cervical and lumbar spine. Clin Imaging. 2001; 24(5):273-5. DOI: 10.1016/s0899-7071(00)00226-6. View

Pappas G, Akritidis N, Bosilkovski M, Tsianos E . Brucellosis. N Engl J Med. 2005; 352(22):2325-36. DOI: 10.1056/NEJMra050570. View

Harman M, Unal O, Onbasi K, Kiymaz N, Arslan H . Brucellar spondylodiscitis: MRI diagnosis. Clin Imaging. 2001; 25(6):421-7. DOI: 10.1016/s0899-7071(01)00334-5. View

El-Desouki M . Skeletal brucellosis: assessment with bone scintigraphy. Radiology. 1991; 181(2):415-8. DOI: 10.1148/radiology.181.2.1924782. View

Lifeso R, Harder E, McCorkell S . Spinal brucellosis. J Bone Joint Surg Br. 1985; 67(3):345-51. DOI: 10.1302/0301-620X.67B3.3997939. View

10.

Madkour M, Sharif H, Abed M, Al-Fayez M . Osteoarticular brucellosis: results of bone scintigraphy in 140 patients. AJR Am J Roentgenol. 1988; 150(5):1101-5. DOI: 10.2214/ajr.150.5.1101. View

11.

Ben Taarit C, Turki S, Ben Maiz H . [Infectious spondylitis. Study of a series of 151 cases]. Acta Orthop Belg. 2002; 68(4):381-7. View

12.

Andriopoulos P, Tsironi M, Deftereos S, Aessopos A, Assimakopoulos G . Acute brucellosis: presentation, diagnosis, and treatment of 144 cases. Int J Infect Dis. 2006; 11(1):52-7. DOI: 10.1016/j.ijid.2005.10.011. View

13.

Tali E . Spinal infections. Eur J Radiol. 2004; 50(2):120-33. DOI: 10.1016/j.ejrad.2003.10.022. View

14.

Sharif H, Clark D, Aabed M, Haddad M, Al Deeb S, Yaqub B . Granulomatous spinal infections: MR imaging. Radiology. 1990; 177(1):101-7. DOI: 10.1148/radiology.177.1.2399306. View

15.

Ariza J, Gudiol F, Pallares R, Viladrich P, Rufi G, Corredoira J . Treatment of human brucellosis with doxycycline plus rifampin or doxycycline plus streptomycin. A randomized, double-blind study. Ann Intern Med. 1992; 117(1):25-30. DOI: 10.7326/0003-4819-117-1-25. View