Estimation of Parameters for a Model of Transmitter Release at Synapses

Overview

Journal Biometrics

Publisher Oxford University Press

Specialty Public Health

Date 1976 Mar 1

PMID 179628

Citations 31

Authors

J Robinson

Affiliations

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Abstract

We consider models for the release of transmitter in response to nerve impulses, where it is assumed that quanta of transmitter are released from some of n sites, the probability of release from any site being p. It is assumed that the quantal size is either a constant or is distributed as a normal or a gamma variate. Observations on both spontaneous potentials and evoked potentials are used to obtain moment estimated of n and p. Large sample estimates of the standard errors of these estimates are given.

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