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Can You Have Dementia with an MMSE Score of 30?

Overview
Publisher Sage Publications
Specialty Neurology
Date 2007 Oct 26
PMID 17959876
Citations 16
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Abstract

Objective: To investigate the possibility that a patient with a diagnosis oF probable Alzheimer's disease (AD) can still obtain a score oF 30/30 on the Mini-Mental State Exam (MMSE).

Design: Chart review. Setting. The McGill University/Jewish General Hospital Memory Clinic.

Participants: Participants were selected From the Memory Clinic's patient database. All underwent comprehensive evaluations, including relevant blood work and a computed tomographic scan or a magnetic resonance imaging scan oF the brain to rule out other causes oF dementia.

Measurements: All patients had one or more neuropsychological evaluation. Data oF all psychometric testing, including the MMSE, were gathered From these visits. Results. Eight patients were Found to meet the criteria oF AD although achieving a score oF 30/30 on the MMSE. Four oF 8 patients achieved this score although they were taking cholinesterase inhibitors.

Conclusion: Although rare, it is possible to achieve a score oF 30/30 on the MMSE even iF a subject is suFFering From a dementing illness.

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References
1.
Beck A, Ward C, Mendelson M, Mock J, ERBAUGH J . An inventory for measuring depression. Arch Gen Psychiatry. 1961; 4:561-71. DOI: 10.1001/archpsyc.1961.01710120031004. View

2.
Folstein M, Folstein S, McHugh P . "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975; 12(3):189-98. DOI: 10.1016/0022-3956(75)90026-6. View

3.
Cobb J, Wolf P, Au R, White R, DAgostino R . The effect of education on the incidence of dementia and Alzheimer's disease in the Framingham Study. Neurology. 1995; 45(9):1707-12. DOI: 10.1212/wnl.45.9.1707. View

4.
Strickland T, Longobardi P, Alperson B, Andre K . Mini-Mental State and Cognistat performance in an older African American sample. Clin Neuropsychol. 2005; 19(1):87-98. DOI: 10.1080/13854040490887243. View

5.
Gauthier S, Panisset M, Nalbantoglu J, Poirier J . Alzheimer's disease: current knowledge, management and research. CMAJ. 1997; 157(8):1047-52. PMC: 1228260. View