Characterization of Mouse Brain and Its Development Using Diffusion Tensor Imaging and Computational Techniques

Overview

Journal Conf Proc IEEE Eng Med Biol Soc

Specialty Biomedical Engineering

Date 2007 Oct 20

PMID 17946946

Citations 13

Authors

Jiangyang Zhang

Linda J Richards

Michael I Miller

Paul Yarowsky

Peter van Zijl

Susumu Mori

Affiliations

Soon will be listed here.

Abstract

Diffusion tensor magnetic resonance imaging (DTI) was used to study mouse brain development from early embryonic stage to adult. DTI provides necessary resolution and superb white matter and gray matter contrast in embryonic and neonatal brains for characterization of morphological changes during mouse brain development. A database and a digital atlas of developing mouse brains based on our DTI results are being constructed. To characterize the spatial and temporal patterns of mouse brain development, we applied landmark based computational techniques to analyze the database.

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