Molecular Detection of Leptospira Interrogans in Human Tissues and Environmental Samples in a Lethal Case of Leptospirosis

Overview

Journal Int J Legal Med

Specialty Forensic Sciences

Date 2007 Oct 19

PMID 17943302

Citations 6

Authors

D Luchini

F Meacci

M R Oggioni

G Morabito

V Damato

M Gabbrielli

G Pozzi

Affiliations

Soon will be listed here.

Abstract

A forensic case of suspected Leptospirosis with fatal course was resolved by the molecular detection of Leptospira interrogans in postmortem human tissues and in environmental samples. Polymerase chain reaction analysis and DNA sequencing confirmed the clinical diagnosis of Weil syndrome, and the death was considered to be an occupational accident with all the legal implications.

Citing Articles

Pathogenic Leptospira contamination in the environment: a systematic review.

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PMID: 38511199 PMC: 10953783. DOI: 10.1080/20008686.2024.2324820.

A systematic review of Leptospira in water and soil environments.

Bierque E, Thibeaux R, Girault D, Soupe-Gilbert M, Goarant C PLoS One. 2020; 15(1):e0227055.

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Critical Knowledge Gaps in Our Understanding of Environmental Cycling and Transmission of Leptospira spp.

Barragan V, Olivas S, Keim P, Pearson T Appl Environ Microbiol. 2017; 83(19).

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Establishment of a leptospirosis model in guinea pigs using an epicutaneous inoculations route.

Zhang Y, Lou X, Yang H, Guo X, Zhang X, He P BMC Infect Dis. 2012; 12:20.

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Leptospirosis diagnosed by molecular DNA detection on skin biopsy.

Doudier B, Laban D, Cazorla C, Fournier P, Parola P, Brouqui P BMJ Case Rep. 2012; 2010.

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