Enantioselective Tsuji Allylations

Overview

Journal Chem Asian J

Specialty Chemistry

Date 2007 Oct 16

PMID 17935094

Citations 74

Authors

Justin T Mohr

Brian M Stoltz

Affiliations

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Abstract

The family of allylation reactions developed by Tsuji in the 1980s are capable of generating tertiary and quaternary carbon stereocenters from several synthetic precursors. Despite the utility of these transformations, they have seen little use in the synthesis of natural products. Recently, the power of these reactions was significantly enhanced by the development of enantioselective versions of these transformations. Applications of these methods to the enantioselective syntheses of natural products and pharmaceutical compounds highlight the importance of these developments.

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