Autism Brain Tissue Banking

Overview

Journal Brain Pathol

Date 2007 Oct 9

PMID 17919127

Citations 15

Authors

Vahram Haroutunian

Jane Pickett

Affiliations

Soon will be listed here.

Abstract

One avenue of progress toward understanding the neurobiological basis of autism is through the detailed study of the post-mortem brain from affected individuals. The primary purpose of autism brain tissue banking is to make well-characterized and optimally preserved post-mortem brain tissue available to the neuroscience research community. In this paper we discuss our current understanding of the criteria for optimal characterization and preservation of post-mortem brain tissue; the pitfalls associated with inadequate clinical and neuropathological characterization and the advantages and disadvantages of post-mortem studies of the brain. We then describe the current status of the brain tissue bank supported by the Autism Tissue Program, including the demographic characteristics of the tissue donors, post-mortem interval, sex, age and the method of preservation. Finally, we provide information on the policies and procedures that govern the distribution of brain specimens by this bank and the nature of the studies that are currently being supported directly by this program.

Citing Articles

Availability of individual proteins for quantitative analysis in postmortem brains preserved in two different brain banks.

Nagaoka A, Hino M, Izumi R, Shishido R, Ishibashi M, Hatano M Neuropsychopharmacol Rep. 2024; 44(2):399-409.

PMID: 38558385 PMC: 11144605. DOI: 10.1002/npr2.12430.

African-American and Caucasian participation in postmortem human brain donation for neuropsychiatric research.

Deep-Soboslay A, Mighdoll M, Jaffe A, Thomas S, Herman M, Sirovatka J PLoS One. 2019; 14(10):e0222565.

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Banking brains: a pre-mortem "how to" guide to successful donation.

Trujillo Diaz D, Hernandez N, Cortes E, Faust P, Vonsattel J, Louis E Cell Tissue Bank. 2018; 19(4):473-488.

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