Alpha 2.0
Login Register
» Articles » PMID: 1790161

Senile Dementia of the Alzheimer Type in the Lundby Study. I. A Prospective, Epidemiological Study of Incidence and Risk During the 15 Years 1957-1972

Overview
Journal Eur Arch Psychiatry Clin Neurosci
Specialties Neurology
Psychiatry
Date 1991 Jan 1
PMID 1790161
Citations 3
Authors
O Hagnell
A Franck
A Grasbeck
R Ohman
L Ojesjo
L Otterbeck
B Rorsman
Affiliations
Soon will be listed here.
Abstract

In spite of the great impact of senile dementia of the Alzheimer type (SDAT) on society, far too little is known about its epidemiology. In this study of a total, normal population from a geographically delimited area in Sweden, Lundby, 2612 persons were examined in 1957 by one psychiatrist (Hagnell). In 1972 the same population was reexamined irrespective of domicile. The incidence and risk of contracting SDAT during the 15 years were calculated. No cases of SDAT were diagnosed before the age of 60 years. The lifetime risk was for men 25.7% and for women 26.2%. When only the very severely impaired were taken into account, the figures were 14.5% in men and 14.6% in women.

Citing Articles

Age-specific incidence rates for dementia and Alzheimer disease in NIA-LOAD/NCRAD and EFIGA families: National Institute on Aging Genetics Initiative for Late-Onset Alzheimer Disease/National Cell Repository for Alzheimer Disease (NIA-LOAD/NCRAD)....

Vardarajan B, Faber K, Bird T, Bennett D, Rosenberg R, Boeve B JAMA Neurol. 2014; 71(3):315-23.

PMID: 24425039 PMC: 4000602. DOI: 10.1001/jamaneurol.2013.5570.

Neuropathological changes in the cerebral cortex of 1258 cases from a geriatric hospital: retrospective clinicopathological evaluation of a 10-year autopsy population.

Giannakopoulos P, Hof P, Mottier S, Michel J, Bouras C Acta Neuropathol. 1994; 87(5):456-68.

PMID: 8059598 DOI: 10.1007/BF00294172.

Senile dementia of the Alzheimer type in the Lundby Study. II. An attempt to identify possible risk factors.

Hagnell O, Franck A, Grasbeck A, Ohman R, Otterbeck L, Rorsman B Eur Arch Psychiatry Clin Neurosci. 1992; 241(4):231-5.

PMID: 1576179 DOI: 10.1007/BF02190258.

References
1.
Rorsman B, Hagnell O, Lanke J . Mortality and age psychosis in the Lundby Study: death risk of senile and multi-infarct dementia. Changes over time in a prospective study of a total population followed over 25 or 15 years. Neuropsychobiology. 1985; 14(1):13-6. DOI: 10.1159/000118194. View
2.
AKESSON H . A population study of senile and arteriosclerotic psychoses. Hum Hered. 1969; 19(5):546-66. DOI: 10.1159/000152266. View
3.
Hagnell O, Lanke J, Rorsman B, Ojesjo L . Does the incidence of age psychosis decrease? A prospective, longitudinal study of a complete population investigated during the 25-year period 1947-1972: the Lundby study. Neuropsychobiology. 1981; 7(4):201-11. DOI: 10.1159/000117852. View
4.
ESSON-MOLLER E, Larsson H, UDDENBERG C, White G . Individual traits and morbidity in a Swedish rural population. Acta Psychiatr Neurol Scand Suppl. 1956; 100:1-160. View
5.
Cooper B, Bickel H . [Prevalence and incidence of dementia diseases in the elderly population. Results of a population-related longitudinal study in Mannheim]. Nervenarzt. 1989; 60(8):472-82. View