Right Liver Lobe/albumin Ratio: Contribution to Non-invasive Assessment of Portal Hypertension

Overview

Journal World J Gastroenterol

Publisher Baishideng Publishing Group

Specialty Gastroenterology

Date 2007 Sep 20

PMID 17879402

Citations 15

Authors

Tamara Alempijevic

Vladislava Bulat

Srdjan Djuranovic

Nada Kovacevic

Rada Jesic

Dragan Tomic

Slobodan Krstic

Miodrag Krstic

Affiliations

Soon will be listed here.

Abstract

Aim: To study the value of biochemical and ultraso-nographic parameters in prediction of presence and size of esophageal varices.

Methods: The study includes selected cirrhotic patients who underwent a complete biochemical workup, upper digestive endoscopic and ultrasonographic examinations. Albumin/right liver lobe diameter and platelet count/spleen diameter ratios were calculated. The correlation between calculated ratio and the presence and degree of esophageal varices was evaluated.

Results: Ninety-four subjects (62 males, 32 females), with a mean age of 52.32 +/- 13.60 years, were studied. Child-Pugh class A accounted for 42.6%, class B 37.2%, whereas class C 20.2%. Esophageal varices (OE) were not demonstrated by upper digestive endoscopy in 24.5%, while OE grade I was found in 22.3% patients, grade II in 33.0%, grade III in 16.0%, and grade IV in 4.3%. The mean value of right liver lobe diameter/albumin ratio was 5.51 +/- 1.82 (range from 2.76 to 11.44), while the mean platelet count/spleen diameter ratio was 1017.75 +/- 729.36 (range from 117.39 to 3362.50), respectively. Statistically significant correlation was proved by Spearman's test between OE grade and calculated ratios. The P values were 0.481 and -0.686, respectively.

Conclusion: The right liver lobe diameter/albumin and platelet count/spleen diameter ratios are non-invasive parameters providing accurate information pertinent to determination of presence of esophageal varices, and their grading in patients with liver cirrhosis.

Citing Articles

RLLB/Alb ratio: a promising noninvasive diagnostic marker in assessing esophageal varices in cirrhotic patients.

Chowdhury M, Islam A, Palit P, Mozibullah M, Sohel M, Khatun M J Clin Lab Anal. 2022; 36(8):e24589.

PMID: 35808890 PMC: 9396198. DOI: 10.1002/jcla.24589.

Accuracy of noninvasive tests in the prediction of portal hypertensive gastropathy in Egyptian patients with cirrhosis.

Amer I, El Shennawy E, El Batea H, Ahmed M, El Sharawy S, Mahros A JGH Open. 2021; 5(2):286-293.

PMID: 33553669 PMC: 7857295. DOI: 10.1002/jgh3.12486.

The Right Liver Lobe Size/Albumin Concentration Ratio in Identifying Esophageal Varices among Patients with Liver Cirrhosis.

Akram M, Soomro M, Magsi M Middle East J Dig Dis. 2019; 11(1):32-37.

PMID: 31049180 PMC: 6488492. DOI: 10.15171/mejdd.2018.125..

Noninvasive Clinical Predictors of Portal Hypertensive Gastropathy in Patients with Liver Cirrhosis.

Mandhwani R, Hanif F, Ul Haque M, Wadhwa R, Hassan Luck N, Mubarak M J Transl Int Med. 2017; 5(3):169-173.

PMID: 29085790 PMC: 5655464. DOI: 10.1515/jtim-2017-0025.

Radiological score for hemorrhage in the patients with portal hypertension.

Ge W, Wang Y, Cao Y, Xie M, Ding Y, Zhang M Int J Clin Exp Pathol. 2015; 8(9):11517-23.

PMID: 26617884 PMC: 4637700.

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