[Leishmania Tropica in Morocco. IV--Intrafocal Enzyme Diversity]

Overview

Journal Ann Parasitol Hum Comp

Specialty Parasitology

Date 1991 Jan 1

PMID 1776781

Citations 27

Authors

F Pratlong

J A Rioux

J Dereure

J Mahjour

M Gallego

E Guilvard

G LANOTTE

J Perieres

A Martini

A Saddiki

Affiliations

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Abstract

Ecoepidemiological analysis of a Moroccan focus of leishmaniasis caused by Leishmania tropica revealed considerable enzymatic diversity. Seven zymodemes belonging to the complex were identified in 149 strains isolated from humans, dogs, and the vector Phlebotomus sergenti. Three distinct subgroups were identifiable, two of which were in turn, composed of three "small variant" zymodemes. The diversity appears to be related to the age of the focus, which may have allowed colonization by zymodemes of different geographic origins. Diversification into "small variants" is apparently the result of recent mutation, possibly associated with genetic exchange.

Citing Articles

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Talimi H, Daoui O, Bussotti G, Mhaidi I, Boland A, Deleuze J Microb Genom. 2024; 10(4).

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Determinants of anthroponotic cutaneous leishmaniasis by case-control study in Morocco.

Amane M, Echchakery M, Daoudi M, Hafidi M, Boussaa S PLoS One. 2022; 17(10):e0266291.

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Environmental, Climatic, and Parasite Molecular Factors Impacting the Incidence of Cutaneous Leishmaniasis Due to in Three Moroccan Foci.

Daoui O, Bennaid H, Kbaich M, Mhaidi I, Aderdour N, Rhinane H Microorganisms. 2022; 10(9).

PMID: 36144314 PMC: 9506065. DOI: 10.3390/microorganisms10091712.

Transmission patterns of Leishmania tropica around the Mediterranean basin: Could Morocco be impacted by a zoonotic spillover?.

Saik I, Benlabsir C, Fellah H, Lemrani M, Riyad M PLoS Negl Trop Dis. 2022; 16(1):e0010009.

PMID: 35025884 PMC: 8757988. DOI: 10.1371/journal.pntd.0010009.

Emerging and Re-Emerging Leishmaniases in the Mediterranean Area: What Can Be Learned from a Retrospective Review Analysis of the Situation in Morocco during 1990 to 2010?.

Kholoud K, Bounoua L, Sereno D, El Hidan M, Messouli M Microorganisms. 2020; 8(10).

PMID: 33008038 PMC: 7650785. DOI: 10.3390/microorganisms8101511.