Nissen Versus Toupet Fundoplication: Results of a Randomized and Multicenter Trial

Overview

Journal Surg Endosc

Publisher Springer

Specialties Gastroenterology
General Surgery
Radiology

Date 2007 Aug 21

PMID 17704884

Citations 28

Authors

E Guerin

K Betroune

J Closset

A Mehdi

J C Lefebvre

J J Houben

M Gelin

P Vaneukem

I El NAkadi

Affiliations

Soon will be listed here.

Abstract

Background: Laparoscopic Toupet fundoplication (TF) is reported to be as effective as Nissen (NF), but to be associated with fewer unfavorable postoperative side-effects. This study evaluates the one- and three-year clinical outcome of 140 randomized patients after a laparoscopic NF or TF.

Patients And Methods: Inclusion criteria included patients over 16 years old with complications of gastro-oesophageal reflux disease (GORD) and persistence or recurrence of symptoms after three months of treatment. Subjects with a previous history of gastric surgery or repeated fundoplication, brachy-oesophagus or severe abnormal manometry results were excluded. Seventy-seven NF and 63 TF were performed. The severity of symptoms was assessed before and after the procedure.

Results: One hundred and twenty-one of the 140 patients after one year, and 118 after three years, were evaluated and no statistically significant clinical difference was observed. The level of satisfaction concerning the outcome of the operation remained high after one or three years regardless of the type of fundoplication performed.

Conclusions: Functional complications after NF are not avoided with TF.

Citing Articles

Determination of causes of post-operative dysphagia after anti-reflux surgery based on intra-operative planimetry.

Al Asadi H, Najah H, Li Y, Marshall T, Salehi N, Turaga A Surg Endosc. 2024; 38(10):5623-5633.

PMID: 39101988 DOI: 10.1007/s00464-024-11101-5.

Long-term efficacy of total versus posterior partial fundoplication in patients with gastro-oesophageal reflux disease: a systematic review and meta-analysis.

Peristeri D, Room H, Tsironis D, Vasilikostas G, Wan A Ann R Coll Surg Engl. 2023; 106(7):569-575.

PMID: 37843095 PMC: 11365733. DOI: 10.1308/rcsann.2023.0046.

LAPAROSCOPIC ANTIREFLUX SURGERY: WERE OLD QUESTIONS ANSWERED? PARTIAL OR TOTAL FUNDOPLICATION?.

Allaix M, Rebecchi F, Bellocchia A, Morino M, Patti M Arq Bras Cir Dig. 2023; 36:e1741.

PMID: 37436210 PMC: 10335357. DOI: 10.1590/0102-672020230023e1741.

Laparoscopic Nissen Versus Toupet Fundoplication for Short- and Long-Term Treatment of Gastroesophageal Reflux Disease: A Meta-Analysis and Systematic Review.

Li G, Jiang N, Chendaer N, Hao Y, Zhang W, Peng C Surg Innov. 2023; 30(6):745-757.

PMID: 36998190 PMC: 10656788. DOI: 10.1177/15533506231165829.

Efficacy of laparoscopic Toupet fundoplication compared to endoscopic and surgical procedures for GERD treatment: a randomized trials network meta-analysis.

Rausa E, Ferrari D, Kelly M, Aiolfi A, Vitellaro M, Rottoli M Langenbecks Arch Surg. 2023; 408(1):52.

PMID: 36680602 DOI: 10.1007/s00423-023-02774-y.

References

Hunter J, Swanstrom L, Waring J . Dysphagia after laparoscopic antireflux surgery. The impact of operative technique. Ann Surg. 1996; 224(1):51-7. PMC: 1235246. DOI: 10.1097/00000658-199607000-00008. View

Zugel N, Jung C, Bruer C, Sommer P, Breitschaft K . A comparison of laparoscopic Toupet versus Nissen fundoplication in gastroesophageal reflux disease. Langenbecks Arch Surg. 2002; 386(7):494-8. DOI: 10.1007/s00423-001-0259-5. View

Wu J, Dunnegan D, Luttmann D, Soper N . The influence of surgical technique on clinical outcome of laparoscopic Nissen fundoplication. Surg Endosc. 1996; 10(12):1164-69; discussion 1169-70. DOI: 10.1007/s004649900271. View

Bell R, Hanna P, Mills M, Bowrey D . Patterns of success and failure with laparoscopic Toupet fundoplication. Surg Endosc. 1999; 13(12):1189-94. DOI: 10.1007/pl00009618. View

DeMeester T, Bonavina L, Albertucci M . Nissen fundoplication for gastroesophageal reflux disease. Evaluation of primary repair in 100 consecutive patients. Ann Surg. 1986; 204(1):9-20. PMC: 1251217. DOI: 10.1097/00000658-198607000-00002. View

Deschamps C, Allen M, Trastek V, Johnson J, Pairolero P . Early experience and learning curve associated with laparoscopic Nissen fundoplication. J Thorac Cardiovasc Surg. 1998; 115(2):281-4; discussion 284-5. DOI: 10.1016/S0022-5223(98)70270-3. View

Hinder R, Klingler P, Perdikis G, Smith S . Management of the failed antireflux operation. Surg Clin North Am. 1997; 77(5):1083-98. DOI: 10.1016/s0039-6109(05)70606-x. View

Lundell L, Abrahamsson H, Ruth M, Rydberg L, Lonroth H, OLBE L . Long-term results of a prospective randomized comparison of total fundic wrap (Nissen-Rossetti) or semifundoplication (Toupet) for gastro-oesophageal reflux. Br J Surg. 1996; 83(6):830-5. DOI: 10.1002/bjs.1800830633. View

Granderath F, Schweiger U, Kamolz T, Pointner R . Dysphagia after laparoscopic antireflux surgery: a problem of hiatal closure more than a problem of the wrap. Surg Endosc. 2005; 19(11):1439-46. DOI: 10.1007/s00464-005-0034-8. View

10.

Pelgrims N, Closset J, Sperduto N, Gelin M, Houben J . What did the laparoscopic Nissen approach of the gastro-oesophageal reflux really change for the patients 8 years later?. Acta Chir Belg. 2001; 101(2):68-72. View

11.

Bessell J, Finch R, Gotley D, Smithers B, NATHANSON L, Menzies B . Chronic dysphagia following laparoscopic fundoplication. Br J Surg. 2000; 87(10):1341-5. DOI: 10.1046/j.1365-2168.2000.01634.x. View

12.

Dallemagne B, Weerts J, Markiewicz S, Dewandre J, Wahlen C, Monami B . Clinical results of laparoscopic fundoplication at ten years after surgery. Surg Endosc. 2005; 20(1):159-65. DOI: 10.1007/s00464-005-0174-x. View

13.

Bretagnol F, Giraudeau B, Mor C, Bourlier P, Gandet O, De Calan L . [Laparoscopic fundoplication for gastroesophageal reflux disease: retrospective study of functional results in 243 patients]. Ann Chir. 2002; 127(3):181-7; discussion 187-8. DOI: 10.1016/s0003-3944(02)00732-0. View

14.

Kamolz T, Bammer T, Wykypiel Jr H, Pasiut M, Pointner R . Quality of life and surgical outcome after laparoscopic Nissen and Toupet fundoplication: one-year follow-up. Endoscopy. 2000; 32(5):363-8. DOI: 10.1055/s-2000-9000. View

15.

Torpy J, Lynm C, Glass R . JAMA patient page. Irritable bowel syndrome. JAMA. 2006; 295(8):960. DOI: 10.1001/jama.295.8.960. View

16.

Lundell L . Surgery of gastroesophageal reflux disease: a competitive or complementary procedure?. Dig Dis. 2004; 22(2):161-70. DOI: 10.1159/000080315. View

17.

Watson D, de Beaux A . Complications of laparoscopic antireflux surgery. Surg Endosc. 2001; 15(4):344-52. DOI: 10.1007/s004640000346. View

18.

Cookson R, Flood C, Koo B, Mahon D, Rhodes M . Short-term cost effectiveness and long-term cost analysis comparing laparoscopic Nissen fundoplication with proton-pump inhibitor maintenance for gastro-oesophageal reflux disease. Br J Surg. 2005; 92(6):700-6. DOI: 10.1002/bjs.4933. View