Crosstalk at the Initial Encounter: Interplay Between Host Defense and Ameba Survival Strategies

Overview

Journal Curr Opin Immunol

Publisher Elsevier

Specialty Allergy & Immunology

Date 2007 Aug 19

PMID 17702556

Citations 15

Authors

Xiaoti Guo

Eric Houpt

William A Petri Jr

Affiliations

Soon will be listed here.

Abstract

The host-parasite relationship is based on a series of interplays between host defense mechanisms and parasite survival strategies. Progress has been made in understanding the role of host immune response in amebiasis. While host cells elaborate diverse mechanisms for pathogen expulsion, amebae have also developed complex strategies to modulate host immune response and facilitate their own survival. This paper will give an overview of current research on the mutual interactions between host and Entamoeba histolytica in human and experimental amebiasis. Understanding this crosstalk is crucial for the effective design and implementation of new vaccines and drugs for this leading parasitic disease.

Citing Articles

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Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors.

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A review of the proposed role of neutrophils in rodent amebic liver abscess models.

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Immune Evasion Mechanisms of Entamoeba histolytica: Progression to Disease.

Begum S, Quach J, Chadee K Front Microbiol. 2015; 6:1394.

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Detection of Entamoeba histolytica in experimentally induced amoebic liver abscess: comparison of three staining methods.

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