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Activation of Human Leucocyte Procollagenase by Rheumatoid Synovial Tissue Culture Medium

Overview
Journal Ann Rheum Dis
Specialty Rheumatology
Date 1975 Dec 1
PMID 176958
Citations 4
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Abstract

Production of a factor activating leucocyte procollagenase by tissue culture of rheumatoid synovium was shown. The activator was isolated, partly purified, and shown to be thermolabile, nondialysable, and had no activity toward casein, haemoglobin, histones, and PZ-peptide. The activity of the activator was partly decreased by trypsin.

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