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Fetal to Adult Stem Cell Transition: Knocking Sox17 off

Overview
Journal Cell
Publisher Cell Press
Specialty Cell Biology
Date 2007 Aug 19
PMID 17693249
Citations 6
Authors
Affiliations
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Abstract

What controls the inherent differences between fetal and adult hematopoietic stem cells (HSCs)? In this issue of Cell, Kim et al. (2007) demonstrate in mice that the endodermal transcription factor Sox17 is required for the maintenance of fetal and neonatal but not adult HSCs.

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