Fetal to Adult Stem Cell Transition: Knocking Sox17 off
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What controls the inherent differences between fetal and adult hematopoietic stem cells (HSCs)? In this issue of Cell, Kim et al. (2007) demonstrate in mice that the endodermal transcription factor Sox17 is required for the maintenance of fetal and neonatal but not adult HSCs.
Fu D, Tan H, Wei J, Zhu C, Jiang J, Zhu Y Tumour Biol. 2015; 36(10):8025-34.
PMID: 25971583 DOI: 10.1007/s13277-015-3547-3.
M A, M H S, M K, B G Int J Organ Transplant Med. 2014; 3(4):183-7.
PMID: 25013644 PMC: 4089296.
Dual lineage-specific expression of Sox17 during mouse embryogenesis.
Choi E, Kraus M, Lemaire L, Yoshimoto M, Vemula S, Potter L Stem Cells. 2012; 30(10):2297-308.
PMID: 22865702 PMC: 3448801. DOI: 10.1002/stem.1192.
Research resource: Genome-wide profiling of progesterone receptor binding in the mouse uterus.
Rubel C, Lanz R, Kommagani R, Franco H, Lydon J, DeMayo F Mol Endocrinol. 2012; 26(8):1428-42.
PMID: 22638070 PMC: 3404303. DOI: 10.1210/me.2011-1355.
Aamar E, Dawid I Dev Dyn. 2010; 239(11):2980-8.
PMID: 20925124 PMC: 3090657. DOI: 10.1002/dvdy.22431.