The Pediatric Chiari I Malformation: a Review

Overview

Journal Childs Nerv Syst

Specialty Pediatrics

Date 2007 Jul 20

PMID 17639419

Citations 61

Authors

R Shane Tubbs

Michael J Lyerly

Marios Loukas

Mohammadali M Shoja

W Jerry Oakes

Affiliations

Soon will be listed here.

Abstract

Background: Both the diagnosis and treatment regimens for the Chiari I malformation (CIM) are varied and controversial. The present paper analyzes the literature regarding this form of hindbrain herniation in regard to definition, anatomy, pathobiology, symptoms, findings, treatment, and outcomes.

Discussions: Appropriate literature germane to the CIM is reviewed and discussed. There is variation in the reported anatomy, outcome, and treatment for children with CIM. Based on the literature, most patients have preoperative symptoms or findings (e.g., syringomyelia) improve no matter what surgical technique is utilized. However, standardized treatment paradigms based on randomized controlled studies are still necessary to elucidate the optimal selection and treatment criteria.

Citing Articles

Delayed dural graft breakdown and intracranial hypotension following posterior fossa decompression and duraplasty for Chiari malformation type I: illustrative case.

Kleyner R, Passman J, Chesler D J Neurosurg Case Lessons. 2025; 9(6).

PMID: 39928928 PMC: 11812444. DOI: 10.3171/CASE24715.

Endoscopic third ventriculostomy (ETV) for Chiari 1 malformation: a systematic review and meta-analysis.

Schimmel S, Ram N, Smith T, Hayman E, Peto I, Piper K Neurosurg Rev. 2024; 47(1):408.

PMID: 39112685 DOI: 10.1007/s10143-024-02623-6.

Individualized Functional Decompression Options for Adult Chiari Malformation With Syringomyelia and A Novel Scale for Syringomyelia Resolution: A Single-Center Experience.

Han S, Hou B, Li Z, Feng F, Li Y, Gao J Neurospine. 2024; 20(4):1501-1512.

PMID: 38171316 PMC: 10762401. DOI: 10.14245/ns.2346626.313.

Decoding Chiari Malformation and Syringomyelia: From Epidemiology and Genetics to Advanced Diagnosis and Management Strategies.

Toader C, Ples H, Covache-Busuioc R, Costin H, Bratu B, Dumitrascu D Brain Sci. 2023; 13(12).

PMID: 38137106 PMC: 10741770. DOI: 10.3390/brainsci13121658.

Unusual Etiology of Chronic Cough and Syncope as Chiari Malformation Type 1.

Patel K, Wani K, Daneshvar A, Omar J Cureus. 2023; 15(6):e40598.

PMID: 37337558 PMC: 10277165. DOI: 10.7759/cureus.40598.

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