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Antibacterial Effect of Bioactive Glasses on Clinically Important Anaerobic Bacteria in Vitro

Overview
Journal J Mater Sci Mater Med
Publisher Springer
Specialty Biomedical Engineering
Date 2007 Jul 11
PMID 17619981
Citations 45
Authors
Outi Lepparanta
Minna Vaahtio
Timo Peltola
Di Zhang
Leena Hupa
Mikko Hupa
Heimo Ylanen
Jukka I Salonen
Matti K Viljanen
Erkki Eerola
Affiliations
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Abstract

Bioactive glasses (BAGs) of different compositions have been studied for decades for clinical use and they have found many dental and orthopaedic applications. Particulate BAGs have also been shown to have antibacterial properties. This large-scale study shows that two bioactive glass powders (S53P4 and 13-93) and a sol-gel derived material (CaPSiO II) have an antibacterial effect on 17 clinically important anaerobic bacterial species. All the materials tested demonstrated growth inhibition, although the concentration and time needed for the effect varied depending on the BAG. Glass S53P4 had a strong growth-inhibitory effect on all pathogens tested. Glass 13-93 and sol-gel derived material CaPSiO II showed moderate antibacterial properties.

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