Transcriptional Partners in Regulatory T Cells: Foxp3, Runx and NFAT

Overview

Journal Trends Immunol

Specialty Allergy & Immunology

Date 2007 Jul 10

PMID 17618833

Citations 34

Authors

Hui Hu

Ivana Djuretic

Mark S Sundrud

Anjana Rao

Affiliations

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Abstract

A general theme in gene regulation is that transcription factors never function alone. Recent studies have emphasized this concept for regulatory T cells, a unique lineage of CD4+ T cells that exert active immune suppression and are essential to maintaining self-tolerance.

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